Basf Aktiengesellschaft

Heinz Isak

Michael Keil

Michael Rack

Bernd Wolf

Reiner Kober

Rainer Seele

Thomas Wettling

Gerhard Hamprecht

Joachim Rheinheimer

Joachim Gebhardt

Horst Wingert

Norbert Goetz

Herbert Bayer

Thomas Zierke

Peter Sch&auml;fer

Reinhard Doetzer

Hubert Sauter

Albrecht Harreus

Thomas Kuekenhoehner

Alexander Weck

Ruth Muller

Norbert Gotz

Horst Mayer

Eckhard Hickmann

Stefan Karbach

Norbert Sendhoff

Dirk Franke

J&ouml;rg Therre

Kirsten Burkart

Remy Benoit

Manfred Munzinger

Jochen Schröder

Michael Dr&ouml;gem&uuml;ller

Guenter Wegner

Markus Nett

Dieter Golsch

Peter Sch{umlaut Over (a)}fer

Martin Lambert

Franz Sch&uuml;tz

Eckhard Hichmann

Michael Drogemuller

Franz Schutz

The invention relates to a process for preparing 2-halopyridinecarboxamides of primary aromatic monoamines I which have a substituent other than hydrogen in the ortho-position to the amino group by reaction of 2-halopyridinecarbonyl chloride II with the aromatic monoamine I, which comprises carrying out the reaction in a solvent mixture comprising water and at least one water-immiscible organic solvent in the presence of none or less than 10 mol %, based on the 2-halopyridinecarbonyl chloride II, of a base other than I or II.

Method for producing 2-halogen-pyridine-carboxylic acid amides

Method for drying phenoxymethylbenzoic acids

Described is a process for the preparation of a particulate tetrahydro-3,5-dimethyl-1,3,5-thiadiazine-2-thione product by combining a first aqueous solution comprising methylammonium N-methyldithiocarbamate with a second aqueous solution comprising formaldehyde, followed by separation and drying of the resulting solid, which comprises combining the first and the second aqueous solutions in such a way that the ratio between the concentrations of dithiocarbamate functions and of formaldehyde is essentially constant in the reaction mixture over time during the duration of the reaction.

Method for the production of a particle-containing preparation of tetrahydro-3,5-dimethyl-1,3,5-thiadiazin-2-thione

Substituted thiopyridines

Substituted thiopyridines of the general formula I

A process for preparing substituted phenylpyridines of the formula I

Process for the production of substituted phenylpyridines

Process and intermediate products for preparing pyridyl-4-fluoroanilines

A process and intermediates for preparing .alpha.-methoxyiminocarboxylic acid methylamides (I) by Pinner reaction of a cyanoketone (II) with an alcohol and subsequent reaction of the resulting ester (IV) with hydroxylamine to give the oxime (V), methylation of (V) to give the oxime ether (VI) and subsequent reaction of (VI) with methylamine: ##STR1##

Preparation of a-methoxyiminocarboxylic acid methylamides and

Preparation of halomethylbenzoyl cyanides

A process for preparing halomethylbenzoyl cyanides I

Preparation of halomethylbenzoly cyanides and novel halomethylbenzoyl

A process for preparing o-chloromethylbenzoyl chlorides of the formula I ##STR1## where m is 0 or an integer from 1 to 4 and X is halogen or C-organic radicals, entails reacting a corresponding lactone of the formula II ##STR2## with thionyl chloride in the presence of a catalyst.

Preparation of o-chloromethylbenzoyl chlorides

Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl

E-Oxime ethers of phenylglyoxylic esters of the formula I ##STR1## X, Y=halogen, alkyl, alkoxy, CF.sub.3, C(.dbd.NOR)R (R=alkyl or alkenyl) are prepared by reacting oximes of the formula II ##STR2## with a methylating agent in an organic diluent, and E-oximes of phenylglyoxylic esters of the formula II are prepared by isomerizing the E/Z-oximes.

Preparation of E-oxime ethers of phenylglyoxylic esters

The preparation of Z-1,2-diarylallyl chlorides of the general formula I ##STR1## in which R.sup.1 and R.sup.2, independently of one another, are hydrogen, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy or a substituted aromatic radical, and n and m are 1, 2 or 3, by dehydrating chlorohydrins of the formula II ##STR2## in which the radicals are as defined above, at up to 50.degree. C. in an inert ether or carboxylic acid ester as solvent and in the presence of a carboxylic anhydride and an organic or inorganic acid, the conversion thereof into azolylmethyloxiranes, and novel intermediates are described.

Stereoselective preparation of Z-1,2-diarylallyl chlorides and the

A process is described for the preparation of cis-2-(1H-1,2,4-triazol-1-ylmethyl)-2-(halophenyl)-3-(halophenyl)oxirane I ##STR1## by epoxidizing Z-3-(1H-1,2,4-triazol-1-yl)-2-(halophenyl)-1-halophenyl)propene II, ##STR2## where halogen is in each case fluorine, chlorine or bromine, which comprises reacting the crude product of the epoxidation with one or more reducing agents, which are added to the reaction mixture in a considerable excess over the amount necessary to destroy any peroxide compounds present.

Preparation of

Growing community of inventors

Mutterstadt, Germany

Heinz Isak