Deutsche Gold- Und Silber-scheideanstalt Vormals Roessler

Degussa Aktiengesellschaft

Degussa - Huls Ag

Degussa Aktiengsellschaft

Evonik Degussa Gmbh

Heinz Friedrich

Helmut Beschke

Gerd Schreyer

Walter Pfefferle

Hermann Lotter

Franz-Ludwig Dahm

Axel Kleemann

Heribert Offermanns

Gunter Prescher

Michael Binder

Wolfram Binder

Klaus-Peter Muller

Klaus-Erich Uffmann

Ulrich Becker

Wolfgang Degener

IIona Walger

Gunther Prescher

Walter Neugebauer

Ulrich Hertz

Wolfgang Leuchtenberger

Herbert Tanner

Dieter Greissinger

Rudiger Schutte

Axel Kleeman

Claas-Jurgen Klasen

Johannes Heilos

Hans-Christian Alt

Heinz Kolb

Wolfgang Heim

Andreas Hofler

Wolfgang Hohn

Claas-Jürgen Klasen

Wolfgang Polzer

Lothar Morl

Andreas Höfler

Henning Holldorff

Kurt Winkler

Herbert Kuhn

Bergstein Wolfgang

Wolfgang Bergstein

Rüdiger SCHÜTTE

Lothar Mörl

The invention provides a feedstuff additive based on a fermentation broth obtained by the fermentation of D-pantothenic acid producing microorganisms. The broth contains D-pantothenic acid, one or more salts of D-pantothenic acid, or mixtures thereof. Conversion of the broth to a solid, free-flowing form is achieved by drying or granulation

Feedstuff additive which contains D-pantothenic acid and/or its salts and a process for the preparation thereof

The invention provides a feedstuff additive based on a fermentation broth which is obtained by the fermentation of D-pantothenic acid producing microorganisms and contains one or more salts of D-pantothenic acid, selected from the group of sodium, potassium, ammonium, magnesium or calcium salts.

A process is disclosed for the fermentative preparation of amino acids, in which an L-lysine producing bacterial strain of the species Corynebacterium glutamicum is cultivated in a nutrient medium and the amino acids can be isolated from the culture medium at the end of fermentation. After the vigorous growth phase, the bacterial culture has at its disposal a smaller quantity of assimilable carbon source than it could metabolize on the basis of the structure of the strain and the quanitity of other necessary supplements provided in the nutrient medium.

Fermentative preparation of amino acids

A process for the preparation of an animal feed supplement based on fermentation broth is disclosed, wherein the supplement contains wholly or predominantly a fermentation product and the other constituents of the fermentation broth, which is characterised in that the fermentation broth is granulated, compacted and dried in a fluidised bed in one step whilst a sufficient amount of energy to obtain a desired particle diameter and a desired bulk density is introduced into the fluidised bed by mechanical device in addition to the energy required to produce the fluidised bed. As a result of this, it is possible, inter alia, to prepare continuously, in a single process step, granules conforming to specification of additives such as lysine, threonine or tryptophan using, in particular, raw fermentation broths as starting substance.

Process for the preparation of an animal feed supplement based on

A process is disclosed for the fermentative preparation of amino acids, in which a strain of the genus Brevibacterium or Corynebacterium producing one or more amino acids is cultivated in a nutrient medium and the amino acids are isolated from the culture fluid at the end of fermentation. After the vigorous growth phase, the bacterial culture has at its disposal a smaller quantity of assimilable carbon source than it could metabolize on the basis of the structure of the strain and the quantity of other necessary supplements provided in the nutrient medium.

Fermentative preparation of lysine with a strain of C. glutamicum

An animal feed additive comprising stable pellets is produced by pelletizing from a fermentation broth containing an animal feed additive with at least 33% by weight of the fermentation products present. The pellets can be produced particularly effectively by pelletizing providing they are built up from at least 30% by weight of fine particles of which at least 70% by weight are smaller than 100 .mu.m in size. The biomass may be completely present, partly present or not present at all in the pellets.

Animal feed additive based on fermentation broth, a process for its

An animal feed supplement and processes for its production which provide an inexpensive, not excessively hygroscopic or sticky supplement amino acid whose content should be standardizable. The animal feed supplement is based on a fermentation broth and contains the predominant proportion of its contents, optionally with the exclusion of part of the biomass. The biomass is preferably present in an amount of at most 10% by weight in the dry state. Proteins are preferably present in a maximum amount of 10% by weight. For the production, the sugar content is adjusted to a maximum of 4 g/l during fermentation, at least towards the end thereof, and at least part of the biomass is optionally removed during the working up.

Animal feed supplement based on a fermentation broth amino acid, a

The invention is directed to a method of producing coarse-crystalline nicotinic acid with a high degree of purity in which 3-cyanopyridine is saponified with aqueous alkali hydroxide and the nicotinic acid is allowed to crystallize out of the alkali nicotinate solution obtained in this manner under the addition of mineral acid at temperatures between 99.degree. and 135.degree. C. The pH is kept above 3.7.

Method of producing-coarse crystalline nicotinic acid with a high degree

For the catalytic reaction of 2-methylpyrazine with ammonia and oxygen to form 2-cyanopyrazine there are used compounds of the elements antimony, vanadium, and oxygen and at least one of the elements iron, copper, titanium, cobalt, manganese, and nickel, whereby the atomic ratio of antimony to vanadium is greater than 1 and which contain besides these compounds a lattice layer silicate and a highly dispersed silica. These catalysts are very selective and result in high yields and high space-time-yields.

Catalysts for the production of 2-cyanopyrazine

For the catalytic reaction of 3-methylpyridine with ammonia and oxygen to form 3-cyanopyridine there are used compounds of the elements antimony, vanadium, and oxygen and at least one of the elements iron, copper, titanium, cobalt, manganese, and nickel, whereby the atomic ratio of antimony to vanadium is greater than 1 and which contain besides these compounds a lattice layer silicate and a highly dispersed silica. These catalysts are very selective and result in high yields and high space-time-yields.

Catalysts for the production of 3-cyanopyridine

Crude nicotinamide is purified by a recrystallization and thereby is particularly freed from nicotinic acid and salts of nicotinic acid. As solvent there is used 2-methylpropanol-1 containing water. The warm solution after dissolving the crude nicotinamide is treated with ion exchangers.

Process for the purification of nicotinic acid amide

Crude nicotinamide is purified by a recrystallization and in this way freed especially from nicotinic acid and salts of nicotinic acid. As solvent there is used a 2-methylpropanol-1 containing water. The recrystallization takes place at a pH between about 7 and 10.

Process for the purification of nicotinic acid amide I

2,3-Cycloalkenopyridines of the formula ##STR1## are prepared by reacting a cycloalkanone or cycloalkenone of the formula ##STR2## with an oxo compound of the formula ##STR3## where Z is an aliphatic carbon chain which is unsubstituted or has hydrocarbon substituents and R.sub.1, R.sub.2 and R.sub.3 are hydrogen or lower alkyl groups and ammonia in the presence of a dehydrating and dehydrogenating catalyst at a temperature of about 250.degree. to 550.degree. C.

Process for the production of 2,3-cycloalkenopyridines

Nicotinamide is prepared from nicotinonitrile by hydrolysis at 120.degree. to 200.degree. C. employing alkali hydroxide.

Process for the production of nicotinamide

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Hanau, Germany

Heinz Friedrich