Herbonis Ag

Dsm IP Assets B.v.

Dsm Nutritional Products Inc.

Heinrich Bachmann

Markus Wyss

Sabrina Autzen

Roland Brugger

Arno Martin Friedlein

Adrian Wyss

Gabriele Margarethe Wirtz

Wolf-Dietrich Woggon

Walter Rambeck

Robert Aebi

The present invention provides a pharmaceutical and/or veterinary composition comprising a retard release formulation of apreparation. The composition further preferably comprises a calcium source. The composition of the invention is suitable to prevent and/or treat hypocalcaemia. Furthermore, the composition is suitable to prevent milk fever in cows. Advantageously, the composition is administered only once before calving so as to prevent the occurrence of mil fever in cows.

Composition comprising solanum glaucophyllum for preventing and/or treating hypocalcaemia and for stabilizing blood calcium levels

The present invention relates to the preparation of an enriched and equilibrated plant extract fromwith an enriched content of 1,25-dihydroxyvitamin D, glycosides and flavonols, particularly quercetin glycosides. The present invention particularly describes a method for preparation of such a plant extract either in industrial or in laboratory scale. The present invention furthermore describes the use of such a plant extract or similar (synthetic) compositions for the prevention and treatment of bone mass reduction-related diseases, such as Osteopenia or Osteoporosis, for the prevention and treatment of Tibial Dyschondroplasis, preferably in poultry, for the treatment of milk fever, and is a dietary supplement for human and veterinary use.

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The present invention relates to the preparation of an enriched and equilibrated plant extract fromwith an enriched content of 1,25-dihydroxyvitamin Dglycosides and flavonols, particularly quercetin glycosides. The present invention particularly describes a method for preparation of such a plant extract either in industrial or in laboratory scale. The present invention furthermore describes the use of such a plant extract or similar (synthetic) compositions for the prevention and treatment of bone mass reduction-related diseases, such as Osteopenia or Osteoporosis, for the prevention and treatment of Tibial Dyschondroplasia, preferably in poultry, for the treatment of milk fever, and as a dietary supplement for human or veterinary use.

Nucleic acid sequences coding for a protein having &#x3b2;,&#x3b2;-carotene 15,15'-monooxygenase activity and their uses in diagnostics, the synthesis of vitamin A and methods for the introduction of the &#x3b2;,&#x3b2;-carotene 15,15&#x2032;-monooxygenase cDNA into host cells are disclosed.

&#x3b2;, &#x3b2;-carotene 15, 15'-monooxygenases, nucleic acid sequences coding therefor and their use

Nucleic acid sequences coding for a protein having &bgr;,&bgr;-carotene 15,15&prime; enzyme activity and their uses in diagnostics, the synthesis of vitamin A and methods for the introduction of the &bgr;,&bgr;-carotene 15,15&prime; enzyme cDNA into host cells are disclosed.

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Wintersingen, Switzerland

Heinrich Bachmann