Lts Lohmann Therapie-systeme Ag

Luye Pharma Ag

Acino Ag

Heiko Spilgies

Andreas Henning

Karsten Heuser

Thomas Hille

Uwe Wortmann

Gabriel Wauer

Rolf Pracht

Holger Piotrowski

Sebastian Braun

Sara Forghani

Roman Hadaschik

Heike Hausner

Eva Werner

Andreas MÜLLER

Franz SCHÖNBACH

The invention relates to a microneedle array, in particular to an applicator system, and to the use thereof for the intradermal delivery of active ingredients in the form of salts, in particular medicinal drugs in the form of salts, wherein this microneedle array is suitable for penetrating the skin of humans or animals, and the microneedles are made of a formulation, containing at least one active ingredient in the form of a salt and at least one biodegradable polymer.

Microneedle array having an active ingredient in the form of salts

The present invention relates to a microneedle system (MNS for short) for the intradermal application of a hepatitis vaccine, namely the antigen HBsAg.

Microneedle system for applying a hepatitis vaccine

The present invention relates to a microneedle system (MNS) for intradermally delivering solutions or formulations. The invention relates to a microneedle system, comprising a cover element (), an active substance container (), a frame (), a microneedle array (MNA) () and a base plate (), wherein the microneedle array (MNA) () is connected to the frame (), and the base plate () has an opening for receiving the microneedle array (), the cover element () and the base plate () are movably connected to one another, the base plate () is joined to a surgical tape (), and the frame () and the base plate () can be linearly displaced with respect to one another. The MNS according to the invention is suitable for intradermally administering medicinal drugs, active substances, pharmaceutical or cosmetic compositions or other substances to an individual, and preferably to a patient, over an extended period.

Microneedle system for administering liquid formulations

A disposable injector with a piston actuation ram is mounted in a housing, is loaded by a spring energy accumulator and can be unlocked by a displaceable trigger device. The piston actuation ram can be supported by a tensioning rod mounted in the housing. The trigger device comprises a trigger ring displaceable relative to the housing. The tensioning rod can be supported directly or indirectly by a bearing surface of the trigger ring. The bearing surface encloses an angle of between ten degrees and forty five degrees with the longitudinal direction of the disposable injector. The point of the angle lies offset with respect to the trigger ring in the triggering direction of the disposable injector. A disposable injector with increased trigger reliability is developed.

Disposable injector with increased triggering reliability

The application provides an injection cannula having an implant which is detachably secured in the cannula. The application also provides a method for detachably securing an implant in an injection cannula.

Implant cannula having an implant and a method for securing implants in an injection cannula

A dermal or transdermal therapeutic system comprising a reservoir that contains at least one active substance, an active substance-permeable membrane which delimits the active-substance reservoir, and a closing layer. The closing layer is impermeable to the active substance at a temperature lying below the skin temperature while being permeable at skin temperature and above.

Reservoir system with closed membrane

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Koblenz, Germany

Heiko Spilgies