Fujisawa Pharmaceutical Company, Ltd.

Heiichi Sakai

Ikuo Ueda

Hiroshi Imanaka

Kazuyoshi Jomon

Daizou Morino

Junzi Hosoda

Production of antibiotic WS-3442 A, B, C, D and E, and their acyl derivatives thereof, the production of antibiotic WS-3442 A, B, C, D and E being a new method by culturing a new species of Streptomyces and their acyl derivatives of said antibiotics being prepared by acylating said antibiotics with an acylating agent. The acyl derivative of antibiotic WS-3442 A, B, C, D and E has antimicrobiological activity and is also useful for intermediate for preparing Cephalosporin derivatives having antimicrobiological activity.

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Ikeda, Japan

Heiichi Sakai