Optiscan Biomedical Corporation

Heidi M Smith

James Roswell Braig

Peter Rule

Julian M Cortella

Martin J Fennell

Daniel S Goldberger

Bernhard B Sterling

Jennifer H Gable

Kenneth I Li

Peng Zheng

Philip C Hartstein

Kenneth G Witte

W Dale Hall

Robert D Gaffney

Roger O Herrera

Mark D Agostino

Mike A Munrow

David Klonoff

Jane J Sheill

A device and method are provided for use with a noninvasive optical measurement system, such as a thermal gradient spectrometer, for improved determination of analyte concentrations within living tissue. In one embodiment, a wearable window is secured to a patient's forearm thereby isolating a measurement site on the patient's skin for determination of blood glucose levels. The wearable window effectively replaces a window of the spectrometer, and thus forms an interface between the patient's skin and a thermal mass window of the spectrometer. When the spectrometer must be temporarily removed from the patient's skin, such as to allow the patient mobility, the wearable window is left secured to the forearm so as to maintain a consistent measurement site on the skin. When the spectrometer is later reattached to the patient, the wearable window will again form an interface between the spectrometer and the same location of skin as before.

Device for capturing thermal spectra from tissue

A method calibrates a monitor that comprises a non-invasive blood constituent monitor and a traditional measurement system. The non-invasive blood constituent monitor includes a thermal gradient inducing element an analyzer window. A traditional monitor output representing a property of a blood constituent is generated by the traditional measurement system. A non-invasive monitor output representing the property of the whole blood constituent is generated by the non-invasive constituent monitor. The traditional monitor output and the non-invasive monitor output are compared to estimate an amount of error. The non-invasive monitor output is corrected by the amount of error.

Calibrator configured for use with noninvasive analyte-concentration monitor and employing traditional measurements

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Union City, CA, United States of America

Heidi M Smith