Sintef Tto As

Life Technologies As

Oslo Universitetssykehus Hf

Sintef

Conpart As

Spermvital As

Heidi Johnsen

Ruth Schmid

Lars Kilaas

Geir Fonnum

Per Martin Stenstad

Synne Larsen

Muhammed Talha Gokmen

Einar Sulheim

Yrr Morch

Nils Pontus Lundberg

Wilhelm Glomm

Kjersti Flatmark

Karianne Giller Fleten

Keith Redford

Geir Klinkenberg

Helge Kristiansen

Elisabeth Kommisrud

Yrr Mørch

Eugenia Mariana Sandru

Justyna Justynska

Wilhelm Robert Glomm

Anne Hege Alm-Kristiansen

Peter Molesworth

Per Nils Pontus Lundberg

Muhammed Talha GÖKMEN

Described herein is a hydrophobic anti-cancer drug encapsulated into poly(alkyl cyanoacrylate) nanoparticles and their use in cancer treatments by intracavitary rout of administration such as intraperitoneal administration.

Drug delivery system for treatment of cancer

The present invention relates to a kit suitable for preparing a sustained release composition, in particular for preparing a sustained release composition comprising spermatozoa embedded within an alginate matrix.

Functionalized kit for preparing hydrogels

The present invention provides a nanoparticle comprising a poly(alkyl cyanoacrylate) homopolymer, or copolymer, at least one active agent and an anionic and radical inhibitor, wherein the anionic and radical inhibitor is a compound having the following formula: wherein R1 is H; and R3, R4, R5, R6 and R7 are independently selected from the group consisting of —H, —OH, C1-C6 alkoxide, C1-C6 alkyl, halides, carboxylic acid, ketone or aldehyde; wherein the anionic and radical inhibitor is present in an amount of 0.001 to 15 wt %, as well as a process suitable for manufacture of the nanoparticle.

Nanoparticles

This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.

Inverse Ugelstad particles

Described herein is an active ingredient encapsulated into poly (alkyl cyanoacrylate) nanoparticles and their use in anti-cancer treatments by intraperitoneal administration.

PACA and cabazitaxel for anti-cancer treatment

Inverse ugelstad particles

A process for the preparation of targeting nanoparticles of a poly(alkyl cyanoacrylate) homopolymer or copolymer, wherein said method comprises, in a single step, the anionic polymerisation of an oil-in-water miniemulsion as herein defined. The invention also relates to nanoparticles produced from said process and to their use in medicine.

Process for preparing stealth nanoparticles

A heat-treated polymer particle comprising an addition polymer core particle which has had swollen and polymerized therein a blend of an aromatic alcohol with an aldehyde or a blend of an aromatic amine or urea with an aldehyde and which has been subsequently heat treated, e.g. to a temperature of at least 150&#xb0; C.

Polymer particle

Growing community of inventors

Trondheim, Norway

Heidi Johnsen