Medtronic, Inc.

University of Minnesota

Covidien LP

Heather Diane Orser

Scott R Stanslaski

Gregory J Loxtercamp

Jadin C Jackson

Robert A Corey

David A Dinsmoor

Kamil Ugurbil

Erik J Peterson

Anand Gopinath

Pierre-Francois Van De Moortele

Carl J Snyder

Lance DelaBarre

Can E Akgun

Jinfeng Tian

John Strupp

Peter M Andersen

Timothy J Denison

Eric J Panken

John Wainwright

David L Carlson

Larry Earl Tyler

Wesley A Santa

J Thomas Vaughan, Jr

Gregor Adriany

Dale G Suilmann

Peter M Anderson

J Thomas Vaughan

Xiaoping Wu

Robert Hocken

Christopher C Olson

Gregor Adiany

Kenneth J Gutzman

Chris E Olson

Lance Delabarre

Chris Olson

Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system may be configured to deliver electrical stimulation therapy to a patient, the electrical stimulation therapy comprising a plurality of therapy pulses at a predetermined pulse frequency over a period of time and deliver, over the period of time, a plurality of control pulses interleaved with at least some therapy pulses of the plurality of therapy pulses. The system may also be configured to sense, after one or more control pulses and prior to an immediately subsequent therapy pulse of the plurality of therapy pulses, a respective evoked compound action potential (ECAP), adjust, based on at least one respective ECAP, one or more parameter values that at least partially defines the plurality of therapy pulses, and deliver the electrical stimulation therapy to the patient according to the adjusted one or more parameter values.

ECAP based control of electrical stimulation therapy

Techniques are described for real-time phase detection. For the phase detection, a signal is correlated with a frequency component of a frequency band whose phase is being detected, and the correlation includes predominantly decreasing weighting of past portions of the signals.

Real-time phase detection of frequency band

A system for detecting strokes includes a sensor device configured to obtain physiological data from a patient, for example brain activity data. A computing device communicatively coupled to the sensor device is configured to receive the physiological data and compare it with reference data. The reference data can be patient data from an opposite brain hemisphere to the hemisphere being interrogated or the reference data can be non-patient data from stroke and normal patient populations. Based on comparison of the physiological data and the reference data, the system indicates whether the patient has suffered a stroke.

Systems and methods for detecting strokes

An example method for controlling delivery of electrical stimulation therapy includes maintaining, by one or more processors of a medical device configured to deliver electrical stimulation to a patient, a counter tied to a clock used by the medical device to deliver the electrical stimulation to the patient; and obtaining, by the one or more processors, one or more representations of sensed electrical signals for the patient that are referenced to counts of the counter. In this example, the method also includes identifying, based on the one or more representations of the sensed electrical signals for the patient, a count of the counter at which stimulation is to be delivered to the patient; and delivering, by the medical device and to the patient, electrical stimulation based on the identified count of the counter.

Precision delivery of electrical stimulation

A magnetic resonance system is disclosed. The system includes a transceiver having a multichannel receiver and a multichannel transmitter, where each channel of the transmitter is configured for independent selection of frequency, phase, time, space, and magnitude, and each channel of the receiver is configured for independent selection of space, time, frequency, phase and gain. The system also includes a magnetic resonance coil having a plurality of current elements, with each element coupled in one to one relation with a channel of the receiver and a channel of the transmitter. The system further includes a processor coupled to the transceiver, such that the processor is configured to execute instructions to control a current in each element and to perform a non-linear algorithm to shim the coil.

High field magnetic resonance

Devices and methods compensate for perturbations in a stimulation signal caused by external conditions such as a magnetic field of an MRI machine so that stimulation therapy may continue in the presence of the external condition. Compensation for the perturbations during a stimulation pulse of a stimulation phase may be provided by using feedback within a stimulation current source. Perturbations during a recharge phase may be addressed by utilizing an active recharge at least when the external condition is present. Furthermore, compensation for perturbations during a recharge pulse of the active recharge phase may be provided by using feedback within a recharge current source. Passive recharge may be used instead of active recharge when the external condition is not present to preserve battery life of the stimulation device. The stimulation device may include a sensor to detect the external condition so that an appropriate mode of recharge may be chosen.

Devices and methods to provide stimulation therapy in the presence of external conditions that induce undesirable perturbations

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Farmington, MN, United States of America

Heather Diane Orser