Koninklijke Philips Corporation N.v.

Ric Investments, Inc.

Heather Dawn Ressler

Michael Thomas Kane

Benjamin Irwin Shelly

Gregory Delano Matthews

Winslow Kevin Duff

Daniel R Martin

Greg Matthews

Uday S Shankar

Mark C Estes

Douglas M Mechlenburg

John H Fiore

Jeff Kepler

Zachary Dean Paul

Mark Dominic D'Angelo

Rochelle E Siirola

Sankarasubrahmani Uday Shankar

Duane Howard Carter, Jr

Sleep apnea can be treated with pressure support therapy using a target pressure level. Detected respiratory events during consecutive multi-session testing period are compared to determine statistical metrics covering gradual changes in therapy efficiency. Adjustments to the target pressure level are based on changes in variability, and maybe made in between therapy sessions.

Pressure adjustment in a respiratory therapy device

Systems and methods for providing respiratory therapy to a subject respond and/or adapt to the detection of an occurrence of a respiratory event. For example, the pressure level of a pressurized flow of breathable gas may be increased responsive to the occurrence of one or more apneas. Based on usage information spanning more than one therapy session, such as the tracked pressure levels, a starting pressure level for a pressurized flow of breathable gas for a subsequent therapy session is determined. The starting level at the beginning of the subsequent therapy session(s) may be the 90% pressure level as determined during the preceding period during which usage information has been gathered.

Starting pressure for respiratory therapy devices

A method of detecting dyssynchrony between a patient and a pressure support system includes receiving patient flow data relating to a flow of gas provided to the patient by the pressure support system, receiving an I/E state signal representing a respiratory phase of the patient as determined by the pressure support system, and analyzing the patient flow data and the I/E state signal and declaring a dyssynchrony for a breath based on at least one of the patient flow data and the I/E state signal. The method includes determining whether at least one of a number of predetermined criterion is satisfied based on at least one of the patient flow data and the I/E state signal, and declaring the dyssynchrony for the breath if it is determined that at least one of the number of predetermined criterion is satisfied.

Patient-ventilator dyssynchrony detection

A monitoring system is used to measure various parameters of the sleep, respiration, and/or other bodily functions of a subject. One or more metrics are calculated that quantify deviation from the mean, trends, changes over time, and/or other changes in the parameters. The metrics are used to generate notifications of these changes that can be conveyed to caregivers and/or other users.

Patient monitoring and exception notification

A pressure support methodology and system that utilizes at least two, and possibly all three, of information relating to (i) airway patency, i.e., the degree to which the patient's airway is open, (ii) the primary cause of the current sleep disordered breathing event, and (iii) the patient's response to previous pressure changes to automatically titrate pressure when presented with a sleep disordered breathing event. In another embodiment, pressure may be automatically titrated based solely on the primary cause of the sleep disordered breathing event.

Automatic pressure titration

A bi-level pressure support system and method of treating disordered breathing that optimizes the pressure delivered to the patient during inspiration and expiration to treat the disordered breathing while minimizing the delivered pressure for patient comfort. The pressure generating system generates a flow of breathing gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expirations. A controller monitor at least one of the following conditions: (1) snoring, (2) apneas, (3) hypopneas, or (4) a big leak in the pressure support system and adjusts the IPAP and the EPAP based on the occurrence of any one of these conditions.

Auto-titration bi-level pressure support system and method of using same

A method of operating a ventilator or pressure support system that automatically determines a timed back up rate for the patient based on the patient's spontaneous breathing patterns. The aggressiveness of the determined rate increases as the patient takes less spontaneous breaths. Also, a method wherein one or more mechanisms are used to determine whether a machine breath should be issued. Each mechanism consists of a basic timing element coupled with one or more logical permits. Both the timing element and each of the one or more logical permits must be satisfied to allow the timing mechanism to trigger a machine breath.

Pressure support system with machine delivered breaths

A bi-level pressure support system and method of treating disordered breathing that optimizes the pressure delivered to the patient during inspiration and expiration to treat the disordered breathing while minimizing the delivered pressure for patient comfort. The pressure generating system generates a flow of breathing gas at an inspiratory positive airway pressure (IPAP) during inspiration and at an expiratory positive airway pressure (EPAP) during expirations. A controller monitor at least one of the following conditions: (1) snoring, (2) apneas, (3) hypopneas, or (4) a big leak in the pressure support system and adjusts the IPAP and the EPAP independently based on the occurrence of any one of these conditions.

A pressure support system and method of treating disordered breathing that optimizes the pressure delivered to the patient to treat the disordered breathing while minimizing the delivered pressure for patient comfort. The controller in the pressure support system operates as a set of prioritized control layers, wherein each control layer competes for control of the pressure generating system to implement a unique pressure control process. The pressure support system also controls the pressure provided to the patient based on the variability of the monitored data and a trend analysis of this data, including an indication of the skewness of the patient's inspiratory waveform.

Auto-titration pressure support system and method of using same

A system including methods and apparatus for treatment of a medical disorder such as obstructive sleep apnea or congestive heart failure. The system involves applying a gain to flow rate of pressurized gas delivered to a patient during inspiratory and/or expiratory phases of a respiratory cycle to deliver the pressurized gas in proportion to the respective gains during inspiration and/or expiration. A base pressure may be applied in addition to the gain-modified pressures and an elevated pressure profile may be employed to assist or control inspiration. The system may be fully automated responsive to feedback provided by a flow sensor that determines the estimated patient flow rate. A leak computer can be included to instantaneously calculate gas leakage from the system. The system may be utilized in connection with conventional continuous positive airway pressure treatments, such as CPAP or bi-level positive airway pressure equipment to effect various beneficial treatment applications.

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New Alexandria, PA, United States of America

Heather Dawn Ressler