Abbvie Inc.

Heath A McDonald

Philip R Kym

Arthur Gomtsyan

Jerome F Daanen

Michael E Kort

Eric A Voight

Erol K Bayburt

Robert G Schmidt

Richard J Perner

Stanley DiDomenico

Jun Chen

Chih-hung Lee

Gregory A Gfesser

Pamela S Puttfarcken

Disclosed herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates, or combinations thereof, wherein X, X, X, X, J, K, L, X, X, R, G, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

TRPV1 antagonists

Disclosed herein are compounds of formula (I), or pharmaceutically acceptable salts, solvates, prodrugs, salts of prodrugs, or combinations thereof, wherein R, R, R, R, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

Disclosed herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates, prodrugs, salts of prodrugs, or combinations thereof, wherein R, R, R, R, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

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Plainfield, IL, United States of America

Heath A McDonald