Ewha University-industry Collaboration Foundation

Hea Young Park Choo

Jin Sung Kim

Young Kook Kim

Chong Ock Lee

Sang Kook Lee

Jin Ah Kim

Hyun Joo Park

Jung Ho Choi

Ju Hee Yoon

Hyeun Wook Chang

Hee Kyung Rhee

Hye Kyung Ju

The present invention relates to benzoxazole derivatives represented by the Formula 1, which has an inhibitory activity against interleukin-6 (IL-6), a method for preparation thereof, and a pharmaceutical composition containing the same. The compound represented by the Formula 1 according to the present invention has a superior inhibitory activity against interleukin-6, and therefore, can be practically applied for prevention and treatment of diseases caused by abnormal interleukin-6 activity.

Benzoxazole derivatives having inhibitory activity against interleukin-6, preparation method thereof, and pharmaceutical composition containing the same

A benzoxazole derivative is disclosed for inhibiting 5-lipoxygenase.

Method for inhibiting 5-lipoxygenase using a benzoxazole derivative

The present invention relates to 1-/2-substituted-1H/-2H-[1,2,3]triazolo[4,5-g]phthalazine-4,9-dione compounds and their pharmaceutically acceptable salts, a process for preparing the compounds and a pharmaceutical composition comprising the compounds. The compounds are shown to effectively inhibit cell proliferation and are thus expected to be used for treatment or prevention or treatment of various cancers or as an ancillary(auxiliary) means of the same.

1-/2-substituted-1H/-2H-[1,2,3]triazolo[4,5-g]phthalazine-4,9-dione compound, process for the preparation thereof and pharmaceutical composition comprising the same

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Seoul, South Korea

Hea Young Park Choo