Jiangsu Xcmg Construction Machinery Research Institute Ltd.

Jiangnan University

Xuzhou Xcmg Port Machinery Co., Ltd.

Xcmg Fire-fighting Safety Equipment Co., Ltd.

He Liu

Geng Xue

Cuijun Jin

Xuemei Zong

Liping Zhang

Bin Zhao

Caihua Ni

Ren Liu

Liwei Xiao

Yimin Zhang

Haijun Zhang

Yilin Lu

Xinyi Dong

Reach stacker

Aerial work platform vehicle

Aerial platform truck

Aerial lift

Cab for digging and loading machine

Hybrid amphiphilic star copolymer nano micelles are prepared in the invention. Cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes is selected as the inorganic part, and L-glutamic benzyl ester&#x2014;five membered ring anhydride is ring-opening polymerized by the initiation of amino groups on the surface of cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes, producing copolymers with cage shaped octa(&#x3b3;-aminopropyl) silsesquioxanes as nucleus and poly (L-glutamic-benzyl ester) as arms. The copolymers reacts with monomethoxy poly (ethylene glycol) carboxylic acid by condensation. Finally, the benzyl groups in the side chains of poly (L-glutamic acid-benzyl ester) are converted into hydrazine groups by acylhydrazination to obtain hybrid amphiphilic star copolymer nano micelles. The micelles can load doxorubicin, they are safe to human body and have good application prospects.

Method for preparation of hybrid amphiphilic star copolymer nano micelles

Growing community of inventors

Jiangsu, China

He Liu