Integrated Biotherapeutics, Inc.

Integrated Biotherapeutic Vaccines, Inc.

Hatice Karauzum

Mohammad Javad Aman

Rajan Prasad Adhikari

Sergey Shulenin

Kelly Lyn Warfield

Frederick Wayne Holtsberg

Tam Nguyen

Thomas Kort

Nils Williston

Jawad Sarwar

Sathya Venkataramani

Shweta Kailasan

Tam Luong Nguyen

The present disclosure provides immunogenic compositions useful in prevention and treatment ofinfection. In particular, the disclosure provides methods of inducing an immune response against a LukAB-expressingmethods of preventing or treatinginfections, and composition for preventing or treatinginfections.

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The present disclosure provides immunogenic compositions useful in prevention and treatment ofinfection. In particular, the disclosure provides delta toxin and phenol-soluble modulin peptides as well as mutants, fragments, variants or derivatives thereof. The disclosure further provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal proteins, e.g., DT, PSM, alpha hemolysin, leukocidin, superantigen, or any fragments, variants, derivatives, or mutants thereof fused together as a single polypeptide in any order.

Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof

The present disclosure provides immunogenic compositions useful in prevention and treatment ofinfection. In particular, the disclosure provides methods of inducing an immune response against a panton-valentine leukocidin (PVL)-expressing, methods of preventing or treatinginfections, and composition for preventing or treatinginfections.

Immunogenic composition comprising Panton-Valentine Leukocidin (PVL) derived polypeptides

The present invention provides immunogenic compositions useful in prevention and treatment ofinfection. In particular, the present invention provides methods of inducing an immune response against an alpha-hemolysin-expressing, methods of preventing or treatinginfections, and composition for preventing or treatinginfections.

Immunogenic composition comprising alpha-hemolysin oligopeptides

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Rockville, MD, United States of America

Hatice Karauzum