Biocure Limited

Johnson and Johnson Vision Care, Inc.

Novartis Ag

Commonwealth Scientific and Industrial Research Organisation

Other

Biocompatibles UK Limited

Navartis Ag

Asfaw, Bruktawit T.

Chaouk, Hassan

Goupil, Dennis W.

Hassan Chaouk

Troy Vernon Holland

Bruktawit T Asfaw

Gordon Francis Meijs

Stephen D Goodrich

Dennis W Goupil

Lucas Latini

Victor Lust

Vincent G McAteer

Brian Schwam

Phillip King Parnell, Sr

Timothy Charles Hughes

Walter R Laredo

Stephen Robert Beaton

Aruna Nathan

Bronwyn Glenice Laycock

Michael J Trezza, Ii

Zhigang Li

Thomas Hirt

Graham M Johnson

John Gerard Steele

Han Cui

Thomas R Karkkainen

Kurt John Moody

Vimala Mary Francis

Maureen J Borgia

Oscar P L Boel

John Stuart Wilkie

Inc Biocure

Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.

Embolic compositions

An interactive fit tool and methodology which may be utilized by an eye care professional to improve the efficiency and final outcome in selecting a pair of contact lenses targeted towards a specific patient visual need in the treatment of presbyopia. The interactive fit tool comprises an application which includes images that would allow a patient to decide if he or she desires balanced visual acuity, near biased visual acuity, or distance biased visual acuity. In addition, the interactive fit tool comprises fit guide tables and performs the calculations for vertex distance and spherical equivalent.

Patient interactive fit tool and methodology for contact lens fitting

Punctal plugs for delivering therapeutic agents have a body, a portion into which the therapeutic agent is held, a winding about the body, and an enlarged portion or anchor at an end.

Punctal plugs

The invention provides punctal plugs for the delivery of active agent to one or both of the tear fluid of the eye and to the nasolacrimal duct. The plugs of the invention have a body, a reservoir contained within the body, and optionally a collarette. The reservoir has at least one opening and contains a polymeric material and at least one active agent.

Punctal plugs for the delivery of active agents

Punctal plugs for delivering therapeutic agents to the eye have a body with a portion into which the therapeutic agent is loaded and a conical anchor portion at an end of the plug.

Described and illustrated are various insertion instruments, cap, plug, method and kit. In one aspect, a cap for a punctal insertion instrument is shown and described. In a further aspect, a punctum plug insertion system that includes the instrument and the cap is provided. In yet a further aspect, a method of releasing a punctum plug from a plug holder is provided. Additionally, a kit that contains the plug insertion instrument, cap, plugs, and instructions for use is provided.

Implantation instruments, system, and kit for punctal implants

A hydrogel string that is useful as a medical device and a method for forming a hydrogel string that utilizes a delivery device in which gelation of a prepolymer is initiated to form a hydrogel, which is then extruded from the device as the hydrogel string.

Hydrogel string medical device

A prosthetic spinal disc nucleus pulposus formed from a hydrogel formed by crosslinking a macromer having a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure and at least two pendant chains bearing crosslinkable groups and an amphiphilic comonomer.

Spinal disc nucleus pulposus implant

Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers.

Hydrogel biomedical articles

Biodegradable biocompatible hydrogels based on poly(vinyl alcohol) and methods for their preparation. The methods for preparation of the hydrogels involve the use of prepolymers. The prepolymers have a PVA backbone and pendant chains that include a polymerizable group. In one embodiment, the pendant chains also include a biodegradable region. In another embodiment, biodegradable regions are incorporated into the hydrogel during its formation.

Degradable poly(vinyl alcohol) hydrogels

Growing community of inventors

Jacksonville, FL, United States of America

Hassan Chaouk