Capsugel Belgium Nv

Hassan Benameur

Dominique Nicolas Cade

Sophie Schreiber

Dwayne Thomas Friesen

Warren Kenyon Miller

Chang Sup Lee

David Thomas Vodak

Keith Hutchison

Jonathan Leonard Cape

Maryline Clauzel

Sophie Robin

Aurélien Sivert

Christopher John Hamilton Porter

Hywel David Williams

Peter John Scammells

Leigh Ford

Cyrille ANDRÈS

The present disclosure relates to delivery systems and methods for increasing the bioavailability and increasing the absorption rate by monolithic enteric capsule administration to humans of active ingredients compared to the bioavailability of active ingredients enterically coated for modified release or gastric protection, particularly acid sensitive active ingredients such as esomeprazole, omeprazole, and other proton pump inhibitors, systems for delivering active pharmaceutical ingredients to humans or animals via monolithic enteric capsules, and improved methods of treating gastrointestinal disorders with such methods and delivery systems.

Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole

The present disclosure relates to aqueous compositions for use in the manufacture of capsule shells and capsules with a functional polymer dispersion. The present disclosure relates to aqueous compositions for use in the manufacture of capsule shells endowed with controlled release properties. The present disclosure also relates to aqueous compositions for use in the manufacture of capsule shells and capsules endowed with moisture barrier properties. The present disclosure also relates to methods of manufacturing the capsule shell and capsules, and to capsule shells and capsules obtained therewith.

Aqueous dispersions of controlled release polymers and shells and capsules thereof

The present disclosure relates to compositions of an aqueous colloidal dispersion of hydroxypropyl methyl cellulose acetate succinate (HPMCAS), and methods for making such colloidal dispersions.

Colloidal dispersion comprising HPMCAS

The present disclosure relates to aqueous compositions for use in the manufacture of capsule shells endowed with bulk enteric properties. The present disclosure also relates, in part, to aqueous dispersions suitable for the implementation of said manufacturing process, and to enteric capsule shells and hard capsules obtained therewith.

Bulk enteric capsule shells

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Eaubonne, France

Hassan Benameur