Centocor, Inc.

The General Hospital Corporation

Harvey J Berger

Peter E Daddona

Rodger P McEver

H William Strauss

Ban A Khaw

Koon Y Pak

Jamshid Maddahi

Daniel Berman

The invention pertains to a method quantitative localization of antimyosin uptake in the myocardium of a patient as an indication of myocardial infarction from a plurality of planar projections displayed simultaneously. The invention also pertains to a method for screening patients with chest pain due to myocardial ischemia to identify patients having a high risk of developing myocardial infarction.

Method for myocardial infarct risk assessment

This invention pertains to a method of imaging atherosclerotic plaque using radiolabeled monoclonal antibodies that are specific for activated platelets or activated endothelial cells. The method is capable of determining the site of endothelial injury. This method involves the administration of a platelet-specific labeled monoclonal antibody or antibody fragment to a patient. The antibody is allowed to accumulate at the plaque site and the plaque is then scanned with a photoscanner. The detected signals are then converted into an image of the plaque.

Methods for imaging atherosclerotic plaque

A method for instantaneous imaging of coronary thrombi is disclosed. A radiolabeled, thrombus-specific antibody or antibody fragment is administered into a coronary artery and the label is detected to obtain a visual image of the thrombus.

Method of imaging coronary thrombi

Method using technetium-99m imaging agents for the study, detection or diagnosis of ischemic, infarcted or diseased tissue. The imaging agents comprise a complex of technetium-99 m and glucarate.

Growing community of inventors

Devon, PA, United States of America

Harvey J Berger