Fox Chase Cancer Center

Institute for Cancer Research

Harvey Hensley

Margie Clapper

Navid Roder

Methods for imaging a tumor in an animal including labeling an organ in the animal with a first detectable label detectable by both fluorescence molecular tomography (FMT) and magnetic resonance (MR) and localized substantially exclusively to the organ, whereupon the labeled organ is capable of use as a first fiducial marker in an image of the animal; administering to the animal a detectably labeled probe that localizes substantially exclusively to a region of interest in the body of the animal; after labeling the organ and administering the detectably labeled probe, imaging the animal with a FMT imager to generate an FMT image, and imaging the animal with a MR imager to generate an MR image; and aligning the FMT and MR images using the first fiducial marker as a first reference point, thereby generating an image comprising a fusion of the FMT image and the MR image.

Systems for fusion of fluorescence molecular tomography and magnetic resonance images

An apparatus is provided, which utilizes an adjustment platform for supporting a subject during the endoscopic examination. Additionally, a method for performing an endoscopic examination is also provided in which an endoscope is inserted into a subject and the endoscope is maintained at a generally fixed position while the position of the subject is adjusted to advance the endoscope into the subject. Further still, a method is provided for estimating the size of sample tissue using an endoscope and a reference element. Based on known parameters of the reference element, the size of the area being examined can be estimated.

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Newtown Square, PA, United States of America

Harvey Hensley