Mitsui Chemicals Agro, Inc.

Haruko Mita

Nobuhiro Kondo

Yoji Aoki

Yoshihisa Tsukamoto

Hideaki Ikishima

Yasuaki Fukazawa

Takeshi Takada

Hidetake Yoshitomi

Hironori Komatsu

A method for producing a 3-(substituted oxy)-4-pyridazinol compound represented by the following general formula (I): comprising reacting a compound represented by the following general formula (III): with a compound represented by the following general formula (IV):MO&#x2014;R&#x2003;&#x2003;(IV). The compound represented by the general formula (I) can be reacted with a compound represented by the following general formula (VI): to provide a compound of general formula (V):  Each of the groups in the formulas is defined. The compounds of general formulas (I) and (V) can be obtained in a high yield and with high selectivity at a low cost, and therefore various functional and active substances can be advantageously synthesized using the compounds as a medicine, an agricultural chemical, a functional material, or an intermediate thereof.

Method for producing a 3-(substituted-oxy)-4-pyridazinol derivative

The present invention provides a method of producing 2-alkyl-3-aminothiophene derivative represented by Formula (4), the method comprising oxidizing a compound represented by the following Formula (1) to produce a compound represented by the following Formula (3) and reducing the compound represented by the following Formula (3): 

Method of producing 2-alkyl-3-aminothiophene derivative

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Omuta, Japan

Haruko Mita