Bayer Aktiengesellschaft

Hartwig Muller

Erwin Bischoff

Klaus Frobel

Martin Scheer

Friedrich Berschauer

Anno De Jong

Olga Salcher

Peter Jeschke

Achim Harder

Gerhard Bonse

Jurgen Scherkenbeck

Michael Londershausen

Johannes-Peter Stasch

Andreas Knorr

Norbert Mencke

Peter Fey

Michael Matzke

Dieter Habich

Arnold Paessens

Rainer Neumann

Christian Kohlsdorfer

Rudi Grutzmann

Jutta Hansen

Peter Kurka

Burkhard Fugmann

Hans-Georg Dellweg

Gert Streissle

Bruno Rosen

Jan-Bernd Lenfers

Jurgen Reefschlager

Karlheinz Weber

Nobert Mencke

Guenther Karmann

Karl-Heinz Weber

Thomas Henkel

The present invention relates to the use of cyclic depsipeptides having 18 ring atoms of the general formula (I) ##STR1## in which R.sup.1 to R.sup.6 have the meaning given in the description, and to their optical isomers and racemates, in medicine and veterinary medicine for combating endoparasites, to their preparation, and to new cyclic depsipeptides having 18 ring atoms.

Cyclic depsipeptides having 18 ring atoms for combating endoparasites

New cyclic depsipeptides having 18 ring atoms, of the general formula (I) ##STR1## in which R represents hydrogen, straight-chain or branched or cyclic alkyl having up to 8 carbon atoms,

Cyclic depsipeptides having 18 ring atoms, and their use for combating

The invention relates to new pseudopeptides having an antiviral action, oft he general formula (I) ##STR1## with the meanings given in the description for the substituents, to a process for their preparation and to their use as antiviral agents, in particular against cytomegaloviruses.

Pseudopeptides having an antiviral action

A method of treating a patient to reduce or prevent an acute or chronic inflammation or an ischaemic state which comprises administering to such patient an effective amount therefor of efomycin A, E or G.

Efomycins A, E and G as antiinflammatory agents

Cardioactive compounds of the formula ##STR1## in which R.sup.1 and R.sup.8 and R.sup.14 and R.sup.15 can be hydrogen or various organic radicals.

Circulation-active dibenzo[1,5]dioxocin-5-ones

The present invention relates to the use of microbiologically prepared compounds and their mixtures, which are called efomycins, as performance promoters in farm animals and processes for their preparation, and furthermore new efomycins and their mixtures as new chemical compounds. The invention also relates to microorganisms which can be used for the preparation of the efomycins and their mixtures.

Efomycins as performance promoters in animals

An animal growth promoter, efomycin G, is obtained by culturing Streptomycetes strain BS 1261. Efomycin G has the following properties:

Efomycin G and it's use as yield promoter in animals

Promoting the growth of animals with a novel compound, named annomycin, by cultivation of Streptomyces strain BS 572, DSM 3817.

Microbiological production of livestock growth-promoting agent

A novel antibiotic for combating bacteria and promoting animal growth is obtained by cultivating Streptomyces strain BA 9.

Antibiotic for animal feeds

Growing community of inventors

Velbert, Germany

Hartwig Muller