Sandoz Gmbh

Kali-chemie Pharma Gmbh

Hartmut Hauth

Samuel David

Peter W Thies

Theodor Fehr

Hans Tscherter

Paul Pfaffli

Dietmar Roemer

Decahydro or octahydro-4-phenyl-cis-isoquinoline derivatives are useful as analgesics, anti-depressants, tranquilizers and sleep inducers.

Organic compounds

Compounds of formula I ##STR1## wherein R.sub.1 is hydrogen or lower alkyl,

Substituted-8-phenylamino ergolines

4-amino-3-methyl-2,9-dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives are disclosed which exhibit analgesic properties, and which have the formula (I) ##STR1## wherein ONE OF R.sub.1 and R.sub.2 represents hydrogen and the other represents an amino group which is substituted by an arylalkyl group or an arylalkenyl group,

2,9-Dioxatricyclo[4,3,1,0.sup.3,7 ]decane derivatives, processes for

The present invention concerns novel 13-bromo-lysergic acid compounds of formula I: ##STR1## wherein R.sub.2 is isopropyl, 1 or 2-methylpropyl or benzyl, useful as agents for the treatment of cerebral insufficiency.

13-Bromo lysergic acid compounds

The present invention concerns heterocyclic compounds of the formula: ##STR1## wherein R.sub.1 is hydrogen or alkyl. R.sub.2 is hydrogen or alkyl and R.sub.3 is substituted or unsubstituted 3-pyridyl, which compounds are useful as salidiuretics and agents for migraine treatment.

N-lysergyl-amino-pyridines

This invention provides new compounds of formula I, ##STR1## wherein R is 3-pyridyl or 3-pyridyl mono- or polysubstituted BY LOWER ALKYL, LOWER ALKOXY, LOWER ALKYLTHIO, PHENOXY, HALOGEN, HYDROXY, OR THE GROUP ##STR2## wherein each of R.sub.1 and R.sub.2 is, independently, hydrogen or lower alkyl, Useful as prolactin secretion inhibitors for the treatment of galactorrhea.

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Riehen, Switzerland

Hartmut Hauth