Centre National De La Recherche Scientifique

Universitè De Montpellier

Institut Curie

Abivax

Takeda Pharmaceutical Company Limited

Baxalta Gmbh

Hartmut Ehrlich

Hans-Peter Schwarz

Friedrich Scheiflinger

Jamal Tazi

Didier Scherrer

Michael Dockal

Ulrich Reineke

Frank Osterkamp

Eberhard Schneider

Randolf Kerschbaumer

Thomas Polakowski

Ulf Reimer

Rudolf Hartmann

Birgit Maria Reipert

Philippe Pouletty

Markus Fries

Hans-Peter Hartung

Sandrine Crabe

Nevena Tzekova

Corinna Hermann

Sebastian Bunk

Patrick Kuery

A compound of Formula (I): or anyone of its metabolites or a pharmaceutically acceptable salt thereof, for use for treating and/or preventing an inflammatory disease, disorder or condition, wherein each R is independently hydrogen, halogen, —CN, hydroxyl, (C-C)fluoroalkyl, (C-C)fluoroalkoxy, (C-C)cycloalkyl, —NO, —NRR, (C-C)alkoxy, phenoxy, —NR—SO—NRR, —NR—SO—R1, —NR—C(═O)—R, —NR—C(═O)—NRR, —SO—NRR, —SOH, —O—SO—OR, —O—P(═O)—(OR)(OR), —O—CH—COOR, (C-C)alkyl; each R' is independently hydrogen, (C1-C3)alkyl, hydroxyl, halogen, —NO, —NRR, morpholinyl, morpholino, N-methylpiperazinyl, (C-C)fluoroalkyl, (C-C)alkoxy, —O—P(═O)—(OR)(OR), —CN, a —NH—SO—N(CH)group, or other groups and further relates to A compound of formula (IV): or a pharmaceutically acceptable salt thereof, for use for treating and/or preventing an inflammatory disease, disorder or condition, wherein V, Z, R, R', n, and n′ are as described above.

Quinoline derivatives for use in the treatment of inflammation diseases

Growing community of inventors

Paris, France

Hartmut Ehrlich