Alza Corporation

Harold F Sanders

Yu-Ling Cheng

Robert M Gale

Edna Sugihara

Lothar W Kleiner

J Richard Gyory

Ronald P Haak

Felix A Landrau

David J Enscore

Shari B Libicki

Robert M Myers

Linda M Hearney

Robert M Meyers

An iontophoretic delivery device (,) is provided. Device (,) has an electronic circuit (,) having electronic components such as batteries (,) mounted thereon. Device (,) also includes a pair of electrode assemblies (,). The electronic circuit (,) is electrically connected to the electrode assemblies (,) using an electrically conductive adhesive (,). The adhesive can also be used to electrically connect two or more electronic components within circuit (,) or to connect an electronic component to the electronic circuit (,). In one practice of the invention, the electrically conductive adhesive (,) functions as an electrode and electrically connects the circuit (,) to an agent-containing reservoir (,). In a further practice of the invention, the electrically conductive adhesive (,) functions as an agent reservoir and contains the agent to be iontophoretically delivered.

Iontophoretic drug delivery apparatus

A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture of sucrose esters of coconut fatty acids, which is predominantly sucrose monolaurate. Preferred embodiments of therapeutic systems for delivering the drug and the sucrose ester employ a matrix containing drug at a concentration above saturation.

Skin permeation enhancer compositions using sucrose esters

A method for enhancing the transdermal flux of a transdermally deliverable drug through intact skin is described in which the drug is delivered simultaneously with sucrose monolaurate or a mixture of sucrose esters of coconut fatty acids, which is predominatly sucrose monolaurate. Preferred embodiments of therapeutic systems for delivering the drug and the sucrose ester employ a matrix containing drug at a concentration above saturation.

A dosage form that coadministers a drug and two percutaneous absorption enhancers to a defined area of the skin is described. The dosage form comprises a body that contains supplies of drug and enhancers and has a basal surface that contacts the area of skin and transmits the drug and enhancers to the area for absorption thereby.

Transdermal drug composition with dual permeation enhancers

A dosage form that coadministers a drug and two percutaneous adsorption enhancers to a defined area of the skin is described. The dosage form comprises a body that contains supplies of drug and enhancers and has a basal surface that contacts the area of skin and transmits the drug and enhancers to the area for absorption thereby.

Growing community of inventors

La Jolla, CA, United States of America

Harold F Sanders