The Upjohn Co.

Harold E Renis

Harvey I Skulnick

Louis L Skaletzky

Mary J Ruwart

Brian Bannister

Clarence DeBoer

The present invention provides a method for inhibiting the synthesis and release of toxins from bacteria which comprises contacting the bacteria with an antitoxic prostaglandin.

Inhibition of bacterial toxin release by prostaglandins

A process for treating viral diseases in humans and animals which comprises administering a therapeutic amount of a compound of the formula ##STR1## the compounds are formulated with pharmaceutical carriers for systemic or local means of administration.

Composition of matter and process

A process for treating DNA viral diseases in humans and animals which comprises administering a therapeutic amount of a compound of the formula ##STR1## the compounds are formulated with pharmaceutical carriers for systemic or local means of administration.

Pharmaceutical compositions of antibiotic U-44,590 and derivatives thereof which can be used to treat Gram-negative and Gram-positive bacterial and viral diseases in humans and animals.

Therapeutic compositions of antibiotic U-44,590 and methods for using

2-(1,3-Diaza-2-cycloalken-2-ylamino)quinazolines and substituted compounds are compounded into local and topical compositions for the treatment of viruses.

Growing community of inventors

Portage, MI, United States of America

Harold E Renis