Beecham-wuelfing Gmbh & Co. Kg

Beecham Wuefling Gmbh & Co.

Harald Maschler

Johannes Jukna

Rolf T Wilke

A method of treatment or prophylaxis of angina in mammals, such as humans, which comprises the administration to the sufferer of an effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof, or a solvate of any of the foregoing: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, A and B are herein defined.

Treatment

A compound of formula (I): ##STR1## or where appropriate a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 each independently represent a moiety of formula (a):

Xanthines

Compounds of the formula (I): ##STR1## and pharmaceutically acceptable acid addition salts thereof, wherein,

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Gronau, Germany

Harald Maschler