Beecham Group Plc

Smithkline Beecham Corporation

Smithkline Beecham Pharma Gmbh

Harald Maschler

Harry Smith

Barbara Ann Spicer

Siegfried B Christensen, Iv

Treatment and compounds

A method for the treatment of cerebrovascular disorders and/or disorders associated with cerebral senility and/or other disorders which method comprises the administration of an effective, non-toxic amount of a compound of formula (I):

Synthesis of 8-substituted xanthines

A method for the treatment of cerebrovascular disorders and/or disorders associated with cerebral senility and/or allergic disorders, proliferative skin disorders, and bronchodilation which method comprises the administration of an effective, non-toxic amount of a compound of formula (I): ##STR1## or if appropriate a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 each independently represent alkyl or a moiety of formula (a):

Substituted xanthines and their use in the treatment of cerebrovascular

A method for the treatment of cerebrovascular disorders and/or disorders associated with cerebral senility and/or other disorders which method comprises the administration of an effective, non-toxic amount of a compound of formula (I): ##STR1## or if appropriate a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 each independently represent alkyl or a moiety of formula (a):

8-substituted xanthine derivatives and method of use thereof

Phenyl-substituted cycloalkenyl compounds useful as PDE IV inhibitors

Growing community of inventors

Nordstemmen, Germany

Harald Maschler