Ganymed Pharmaceuticals Ag

Johannes Gutenberg-Universität Mainz

Astellas Pharma Gmbh

Ganymed Pharmaceuticals Gmbh

Tron—translationale Onkologie An Der Universitátsmedizin Der Johannes Gutenberg—universität Mainz Gemeinnützige Gmbh

Tron—translationale Onkologie An Der Universitat

Johannes Gutenberg-universität Mainz, Vertreten Durch Den Präsidenten

Harald-Gerhard Geppert

Ugur Sahin

Stefan Fritz

Dirk Usener

Gunda Brandenburg

Anja Kristina Schröder

Özlem Türeci

Phillippe Thiel

Christoph Uherek

Ozlem Tureci

Michael Koslowski

Oezlem Tuereci

Anja Kristina Schroder

Philippe Thiel

Stephan Fritz

Cristoph Uherek

Anja Kristina Schroeder

The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD18, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.

Monoclonal antibodies against Claudin-18 for treatment of cancer

Monoclonal antibodies against claudin-18 for treatment of cancer

According to the invention, gene products expressed in a tumor-associated manner and the nucleic acids coding therefor were identified. The invention relates to the therapy and diagnosis of diseases wherein said gene products expressed in a tumor-associated manner are aberrantly expressed. The invention also relates to proteins, polypeptides and peptides which are expressed in a tumor associated manner and to nucleic acids coding therefor.

Antibody to genetic products differentially expressed in tumors and the use thereof

The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing CLD1 8, including tumor-related diseases such as gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder.

Genetic products differentially expressed in tumors and the use thereof

Growing community of inventors

Hannover, Germany

Harald-Gerhard Geppert