Boehringer Mannheim Gmbh

Aventis Pharmaceuticals Products Inc.

Harald Funke

Gerd Assmann

Christoph Kessler

Rudiger Rueger

Stephan Rust

Patrice Denefle

Patrick Benoit

Nicolas Duverger

Eric Bruckert

Jean-Charles Fruchart

G&eacute;rald Luc

G&eacute;rard Turpin

The present invention relates to variants of the human apolipoproteine A-I comprising a cystein in position 151, the corresponding nucleic acids and the vectors containing them. It also relates to pharmaceutical compositions comprising said elements and their utilization, particularly in genic therapy.

Variants of apolipoprotein A-I

Method of detecting nucleic acids whose nucleotide sequences differ from one another at a position X. The method uses a set of oligonucleotides where the nucleotides found at position X are complementary to a variant nucleic acids only at this position X. However, with respect to the position of another mismatch Y, the nucleotide sequences thereof differ from one another. The invention further addresses reagents for performing the methods as well as reagents and applications of the method.

Method of detecting variant nucleic acids using extension

Method of detecting variant nucleic acids

Growing community of inventors

Munster, Germany

Harald Funke