Norsk Hydro, A.s.

Norskhydro Asa

Pronova Biopharma Norge As

Epax Norway As

Other

Pronova Blopharm Norge As

Norsk Hydor Asa

Pronova A.s

Basf As

Epax As

Harald Breivik

Olav Thorstad

Knut Helkangs Dahl

Hans Einar Krokan

Lola Irene Sanna

Michel Perrut

Bernt Bo Slashedrretzen

Tanja Vojnovic

Berit Annie Aanesen

Harald Svensen

Gudmundur G Haraldsson

Bernt Borretzen

Wieslaw Majewski

Vidar Moen

Kaare H Bonaa

Kaare Harold Bo Slashednaa

Kaare Harald Bo Slashednaa

Roger-Marc Nicoud

Charlotte Jacobsen

Iren Merete Skjåstad Stoknes

Kari Aasb&oslash;

Elin Kul&aring;s

Fred Olav Libnau

Iren Merete Stoknes

Elin Kulas

Kari Aasbo

The present application relates to compositions for treatment of eye disorders, particularly for treatment of dry eye disease (DED) and meibomianitis, wherein the composition comprises very long chain polyunsaturated fatty acids. Further, the invention provides a method for treatment of DED and meibomianitis of a subject, comprising administering to the subject a composition comprising very long chain polyunsaturated fatty acids derived from natural oils. The compositions for use are suitable for oral and local applications.

Composition for treatment of dry eye disease and meibomianitis

A method of producing a composition comprising a high concentration of very long chain polyunsaturated fatty acids (VLCPUFAs) from natural oils such as fish oil, squid oil, algal oil and krill oil. In addition, a composition comprising a high concentration of very long chain polyunsaturated fatty acids isolated from such natural sources; as well as to a process for isolating separate fractions of very long chain polyunsaturated fatty acids having identical chain lengths but different degrees of unsaturation from such highly concentrated compositions is disclosed.

Very long chain polyunsaturated fatty acids from natural oils

In one aspect, the present invention is directed to a method for obtaining an enriched composition of long chain monounsaturated fatty acids from an oil composition, typically a fish oil composition, comprising both long chain monounsaturated fatty acids and long chain polyunsaturated fatty acids. In another aspect, the present invention is directed to a composition comprising at least 70% by weight of long chain monounsaturated fatty acids.

Long chain monounsaturated fatty acid composition and method for the production thereof

The present invention relates to compositions suitable for improving oxidative stability of marine oils, marine oils having improved oxidative stability as well as methods for manufacturing such compositions.

Antioxidant composition for marine oils comprising tocopherol, rosemary extract, ascorbic acid and green tea extract

The present disclosure relates generally to processes for concentrating omega-3 fatty acids from a fatty acid oil mixture with an aqueous silver salt, such as an aqueous AgNOsolution.

Process for concentrating omega-3 fatty acids

The present invention relates to a process for preparing compositions of high concentrations of omega-3 fatty acids from krill. Furthermore, the invention relates to a composition comprising high concentrations of omega-3 fatty acids, and a lipid fraction from krill comprising high amounts of fatty acids with chain length C14 and C16.

Krill oil process

The present invention relates to a method for stabilizing vegetable, marine and single cell oils/oil concentrates as well as pigments like astaxanthin and canthaxanthin with regard to oxidation. It also relates to a feed for salmonids, and a method for optimising the effect of the pigment in feed for salmonids. Furthermore, the invention relates to a health care product and a composition for prophylaxis or therapeutical treatment. Essential features by the invention are treatment by or presence of amines/amides.

Stabilisation  of pigments and polyunsaturated oils and oil concentrates

The invention relates to a process for decreasing the amount of environmental pollutants in a mixture comprising a fat or an oil, being edible or for use in cosmetics, the fat or oil containing the environmental pollutants, which process comprises the steps of adding a volatile working fluid to the mixture, where the volatile working fluid comprises at least one of a fatty acid ester, a fatty acid amide, a free fatty acid and a hydro-carbon, and subjecting the mixture with the added volatile working fluid to at least one stripping processing step, in which an amount of environmental pollutant present in the fat or oil, being edible or for use in cosmetics, is separated from the mixture together with the volatile working fluid. The present invention also relates to a volatile environmental pollutants decreasing working fluid, for use in decreasing an amount of environmental pollutants present in a fat or oil, being edible or for use in cosmetics. In addition, the present invention relates to a health supplement, a pharmaceutical and an animal feed product prepared according to the process mentioned above.

Pharmaceutical composition comprising low concentrations of environmental pollutants

The invention relates to a process for decreasing the amount of environmental pollutants in a mixture comprising a fat or an oil, being edible or for use in cosmetics, the fat or oil containing the environmental pollutants, which process comprises the steps of adding a volatile working fluid to the mixture, where the volatile working fluid comprises at least one of a fatty acid ester, a fatty acid amid, a free fatty acid and a hydro-carbon, and subjecting the mixture with the added volatile working fluid to at least one stripping processing step, in which an amount of environmental pollutant present in the fat or oil, being edible or for use in cosmetics, is separated from the mixture together with the volatile working fluid. The present invention also relates to a volatile environmental pollutants decreasing working fluid, for use in decreasing an amount of environmental pollutants present in a fat or oil, being edible or for use in cosmetics. In addition, the present invention relates to a health supplement, a pharmaceutical and an animal feed product prepared according to the process mentioned above.

Process for decreasing environmental pollutants in an oil or a fat

This invention relates to a new silage aid, process for preparation of this silage aid and use of the silage aid. The silage aid comprises at least one antioxidant selected from the group 2,6-di-tert-butyl-4-methylphenol (BHT), 3-tert-butyl-4-hydroxyanisole (BHA), tert-butylhydroquinone (TBHQ), tocopherol and gallates; at least one short chain caboxylic acid; and optionally at least one salt of said acid. These andoxidants are food approve. The present silage aid is useful for preservation of organic by-products, and particularly for protection of fish oil during a fish silage process.

Silage aid, process for preparing this silage aid and use of this silage aid

This invention relates to a new pigment in feed for salmonides, a new feed comprising this pigment and use of this pigment. The pigment comprises a diester of astaxanthin prepared with an omega-3 fatty acid and/or a short chain carboxylic acid. By this invention a pigment for feed to salmonides that is more stable and biologically more effective than free astaxanthin and commercially available astaxanthin product, is provided.

Pigment

The present invention relates to a method for stabilizing vegetable and animal oils as well as pigments like astaxanthin and canthaxanthin with regard to oxidation. It also relates to a feed for salmonids, and a method for optimising the effect of the pigment in feed for salmonids. Essential feature by the invention are treatment by or presence of urea.

Stabilization of pigments and polyunsaturated oils

Polyunsaturated fatty acids, as free fatty acids, fatty acid esters or fatty acid amides, especially EPA and/or DHA, DPC 9/02, are recovered from urea adducts, such as obtained as by-products in the processing of fish and other oils, by treatment with a subcritical or supercritical fluid.

Recovery of polyunsaturated fatty acids from urea adducts

A composition containing polyunsaturated fatty acid glycerides is purified by means of supercritical fluid fractionation in one or more countercurrent columns operated either with internal reflux achieved by a temperature gradient along the column or with an external reflux achieved through external regulation of the pressure, and using as the solvent a mixture of supercritical CO,and a polar co-solvent. Oligomeric and malodorous impurities in particular can be successfully removed by this process, which also can, if desired, be followed, or preceded, by another supercritical fluid fractionation with supercritical C0,under conditions adjusted so as to favor fractionation of the glyceride components.

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Porsgrunn, Norway

Harald Breivik