Merck Sharp + Dohme Corp.

Hao Wang

Jing Su

John P Caldwell

Christina B Madsen-Duggan

Ginny Dai Ho

Marc A Labroli

Sookhee Nicole Ha

Mihir Mandal

Shu-Wei Yang

Christine Yang

Zheng Tan

Terry Roemer

Christopher Michael Tan

Sang Ho Lee

Sandra J Koseoglu

Haifeng Tang

Fa-Xiang Ding

Weidong Pan

Jianping Pan

Reynalda De Jesus

Charles J Gill

Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a &#x3b2;-lactam antibiotic.

Benzimidazoles and indoles as taro inhibitors

Oxazolidinones as TarO inhibitors

Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a &#x3b2;-lactam antibiotic. 

Oxazolidinones as taro inhibitors

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Scotch Plains, NJ, United States of America

Hao Wang