University of Michigan

Ascentage Pharma (Suzhou) Co., Ltd.

Ascentage Pharma Group Corp Limited

Cisco Technology, Inc.

Jiangsu Taihu Planning and Design Institute of Water Resources Co., Ltd.

Tongji Artificial Intelligence Research Institute (Suzhou) Co. Ltd.

Ascentage Pharma Co., Ltd.

Hao Chen

Shaomeng Wang

Chao-Yie Yang

Yu Jing

Yunlong Zhou

Guozhi Tang

Fei Wang

Jianyong Chen

Zhen Li

Chao Li

Lingling Jiao

Wenming Chen

Dongbo Li

Yibing Guan

Runnian Wang

Yufeng Chang

Ben Lv

Pinru Cheng

Chengzhe Wu

Fang Wu

Leilei Zhao

Binghua Sheng

Ye Chen

Shi Cheng

Wenliang Hu

Xiaofeng Gu

Jianzhong Yu

Ruoyu Deng

A vision-and-laser-fused 2.5D map building method includes: calculating inter-image frame transformation according to an RGB-D image sequence to establish a visual front-end odometer; taking a visual front-end initial estimation as an initial value of scanning matching, and performing laser front-end coarse-grained and fine-grained searches; performing loop closure detection, and performing back-end global optimization on a 2.5D map according to a detected closed loop; and performing incremental update on visual feature dimensions of the 2.5D map, and performing occupation probability update on grid dimensions. The 2.5D map is built using a method of fusing a laser grid and visual features, and compared with a pure laser map and a pure visual map, richness of dimensions is improved, and completeness of information expression is improved; the 2.5D map building method is not influenced by single sensor failure, and can still stably work in a scenario of sensor degradation.

Vision-and-laser-fused 2.5D map building method

Disclosed is compound of formula I and the pharmaceutically acceptable salts and solvates thereof, wherein R, R, R, R, L, L, #, #, # are as defined as set forth in the re) specification. Disclosed is compound of formula I for use to treat a condition or disorder responsive to Mcl-1 inhibition such as cancer.

Macrocyclic indoles as Mcl-1 inhibitors

Provided are compounds represented by Formula (I-A) and the pharmaceutically acceptable salts and solvates thereof, wherein R, R, R, R, R, X, Y, Z, Z, W, and (aa) are as defined as set forth in the specification. Provided are also compounds of Formula (I-A) for use to treat a condition or disorder responsive to Mcl-1 inhibition such as cancer. 

Macrocyclic spiroethers as Mcl-1 inhibitors

Disclosed are a bailer-type long-shaft pump () and an associated pump station (). The long-shaft pump comprises a bailer vehicle (), a long shaft (), a bearing (), a transmission device () and an electric motor (). One end of the long shaft () successively passes through the bearing () and the transmission device () so as to be in transmission connection with a drive shaft of the electric motor (). The pump station () comprises a pump station foundation (), several equipment rooms () transversely distributed at intervals and constructed on the pump station foundation (), and two ends of the long shaft () are supported on side walls of two adjacent equipment rooms. The bailer-type long-shaft pump achieve large water flow and low lift, the pump station is space-saving, has shorter construction cycle, and reduces investment and operation costs.

Bailer-type long-shaft pump and application thereof

A video conference session is established between a plurality of meeting clients, where each meeting client includes a computing device that communicates via a network and at least one host server with computing devices of other meeting clients. A presenter is established for the video conference session, where the presenter includes at least one of the meeting clients, and audio and video content generated from the presenter is provided to other meeting clients within a base room of the video conference session, where the presenter provides audio content to the base room in a first language. In response to at least one meeting client selecting a translation of the audio content from the presenter from the first language into a second language, audio content is provided to the at least one meeting client in the second language during the ongoing video conference session.

Simultaneous language interpretation during ongoing video conferencing

Growing community of inventors

Suzhou, China

Hao Chen