Behringwerke Aktiengesellschaft

Hansjorg Ronneberger

Norbert Heimburger

Peter Fuhge

Klaus-Dieter Hungerer

Manfred Schick

Klaus-Dieter Bremecker

A description is given of a one-component tissue adhesive containing, in aqueous solution, fibrinogen, F XIII, a thrombin inhibitor, prothrombin factors, calcium ions and, where appropriate, a plasmin inhibitor and of a process for the production thereof. This adhesive can be reconstituted from a freeze-dried form with water. It can contain all active substances in pasteurized form and is then free of the risk of transmission of hepatitis and HTLV III.

One-component tissue adhesive and a process for the production thereof

A pharmaceutical which is for nasal administration and contains a high molecular weight active compound and a gel-forming agent and, where appropriate, auxiliaries is described. High molecular weight active compounds of this type are, in particular, immunogens or other pharmacologically effective substances. In addition, a process for the preparation of a pharmaceutical of this type and its use are described.

Pharmaceutical which can be administered nasally, a process for its

A method for the treatment of thromboembolisms in a patient, said method consisting essentially of intravenously administering to said patient an effective amount of a complex formed between streptokinase and plasminogen in a mol ratio from 2:1 to 1:2 in combination with a physiologically tolerable aqueous liquid diluent.

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Marburg, Germany

Hansjorg Ronneberger