Bayer Aktiengesellschaft

Hansjorg Durr

Axel Kretschmer

Burkhard Mielke

Eckhard Schwenner

Udo Stropp

Christoph Schwemler

Winfried Kosch

Roberto Correa

Hans-Robert Hehnen

Thorsten Potter

Lothar Helbig

The present invention relates to compounds of the general formula (I), ##STR1## in which the radicals have the meaning given in the description, to processes for their preparation and to their use as medicaments.

Nucleic acid-binding oligomers for therapy and diagnosis

The method permits the non-destructive analytical detection and/or the quantification of viruses or viral particles (analytes) in a liquid sample matrix containing organic or inorganic minor constituents, in particular protein moieties and/or nucleotides and/or other viruses. To this end the viruses or the viral particles are separated from the protein moieties and/or nucleotides in the sample matrix using capillary electrophoresis and at the same time the electropherogram associated therewith is recorded. The fractions assigned to the analytes can then be identified as virus peaks in the electropherogram by spectroscopic interpretation with the aid of characteristic maxima. For better identification, a reference sample of a known virus or of a known viral particle can be added to the sample matrix.

Method for the analytical separation of viruses

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Burscheid, Germany

Hansjorg Durr