Hoffmann-la Roche Inc.

Affymetrix, Inc.

Chemspeed Ltd.

Cybio Ag

Hansj&ouml;rg Tschirky

Christof Fattinger

Ulrich Certa

Rolf G&uuml;ller

S&eacute;raphin Munch

Paul Hadvary

Thilo Enderle

Philippe Jablonski

Thomas Gees

Gerhard Flury

Hans-Peter Hirt

A compound handling system handles a multiplicity of chemical or biological compounds or samples, and is especially adapted for high throughput screening of compounds that are stored and handled in aliquotted form. Aliquots are contained in individual containers and the containers are arranged in racks having holding spaces open at opposite ends. Insertion and removal of the containers is effected in either direction of movement, and each container may be sealed with foil to protect its integrity.

Compound handling system

A washing system comprises a support for holding several cartridges. Each cartridge has a chamber with an inlet and an outlet. Wash blocks are movably coupled to the support, each having two needles for penetrating the inlet and the outlet of a respective cartridge when the wash blocks are moved towards the support. Tubing is coupled to the needles for flowing liquid through the chamber of the cartridge.

Cartridge washing system and methods

The present invention relates to a medical device adhering to the skin comprising a housing with a rigid base fixable on a patient's skin by means of an adhesive layer which has an adhesive surface, essentially co-extensive with the base, contacting the skin and which is fixed to the base by a reduced surface in comparison to the adhesive surface contacting the skin.

Medical device adhering to the skin

A device for carrying out a multiplicity of chemical, biochemical or physical processes in parallel has a plurality of switching blocks ( ), to which a multiplicity of reaction vessels ( ) are removably fastened. Liquids, gases and/or solids can be supplied to and/or extracted from the reaction vessels ( ) through the switching blocks ( ). Each switching block ( ) comprises a gas duct plate ( ) and a functional plate ( ) which is arranged so that it can be displaced on it. The gas duct plate ( ) has a multiplicity of through-holes, a gas duct and a multiplicity of gas duct holes extending from the gas duct to the functional plate ( ) and the functional plate ( ) has a multiplicity of through-holes and depressions open to the gas duct plate ( ). Depending on the position of the plates, through-holes, depressions or sealing surfaces of the functional plate ( ) are located opposite to through-holes and gas duct holes of the gas duct plate ( ).

Device for conducting plurality of chemical, biochemical or physical procedures in parallel

An apparatus for providing temperature control and agitation to a plurality of reaction vessels comprises a plurality of elastic receptacles on a block, each receptacle supporting a reaction vessel below its neck, and, a plurality of elastic couplings, each coupling retaining a reaction vessel at its neck section. A flow channel is provided within the block to transfer a liquid temperature control medium to the reaction vessels. The flow channel is routed to each receptacle individually, thereby supplying the medium directly to the corresponding reaction vessel. A shaking arrangement is provided to agitate the reaction vessels by moving the receptacles horizontally relative to the couplings. The greatest deflection of each reaction vessel occurs at its base, while the neck sections are subjected to slight movement.

Device for holding reaction vessels which can be thermally adjusted and agitated

A microdispensing system is useful for the open-jet dispensing of liquids. A valve having a valve chamber is bounded by an impermeable elastic membrane and is filled with the liquid for dispensing. One or more liquid supply lines lead to the valve chamber. An outlet closed from the exterior by the membrane in the position of rest leads from the chamber to a dispensing nozzle. An actuator chamber is disposed on the other side of the membrane. In the actuator chamber, an electromechanical drive is connected to the membrane for the purpose of briefly lifting the membrane from the outlet. The actuator chamber is closed in such manner that it can be subjected to a pressure differing from atmospheric pressure.

Growing community of inventors

Ettingen, Switzerland

Hansjörg Tschirky

Growing community of inventors

Ettingen, Switzerland

Hansj&ouml;rg Tschirky

Hansjörg Tschirky