Basf Aktiengesellschaft

Basf Se Corporation

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Basfaktiengesellschaft

Hansgeorg Ernst

Joachim Paust

Wolfgang Siegel

Stefan Haefner

Rajan Hollmann

Ernst Buschmann

Hartwig Schröder

Klaus Ditrich

Heinz Eckhardt

Johann-Peter Melder

Wilhelm Rademacher

Bernhard Hauer

Johann Jung

Christian Bittner

Walter Dobler

Udo Rheude

Wolfgang Krause

Werner Hoffmann

Walter Himmele

Michael Puhl

Michael Breuer

Wolfgang Schrof

Frank Funke

Hagen Jaedicke

Frank Dietsche

Marco Thyes

Andrea Misske

Andreas Keller

Melanie Weingarten

Wolfgang Krieg

Matthias Frauenkron

Johannes Grimmer

Friedrich Vogel

Bernhard Schulz

Heinz Etzrodt

Wolfram Burst

Karl Beck

Klaus Henrich

Ingo Münster

Martin Scholtissek

Aline Raddatz

Daniela Klein

Christoph Wegner

Ekkehard Winterfeldt

Henning-Peter Gehrken

Hartwig Schroder

Angelika-Maria Pfeiffer

Hartmut Leininger

Reinhard Kaczmarek

Ludwig Völkel

Gregory Von Abendroth

Hans Gurski

Reinhard W Hoffmann

Peter Munster

Wolfram Schmidt

Christian Köpsel

Wolfgang Littmann

Thomas M&uuml;ller

Wittko Francke

J&uuml;rgen Koppenh&ouml;fer

Otto Worz

Karin Schein

Arno Kochner

Guenter H Knaus

Wolf Engels

Gunter Dauwel

Armin Bertram

Stefan Benson

Jesper Feldthusen Jensen

Jürgen Koppenhöfer

Hartwig SCHRÖDER

The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography.

Microbial succinic acid producers and purification of succinic acid

The present invention relates to new types of processes for the improved preparation of homofarnesol, in particular of (3E,7E)-homofarnesol and homofarnesol preparations with an increased content of (3E,7E)-homofarnesol (also referred to as all E-homofarnesol).

Process for the preparation of (3E, 7E)-homofarnesol

The present invention relates to the preparation of oxovinylionol and its O-protected derivatives of the formula I in which R is hydrogen or an OH protecting group, for example a group Si(R), by reacting a compound of the general formula II in which R has the meanings given above for formula I, i.e. &#x3b2;-vinyl ionol (formula II, R=hydrogen) or an O-protected derivative thereof (formula II, R&#x2550;OH protecting group) with an oxidant in the presence of at least one transition metal, where the oxidant comprises at least one oxygen-containing compound which is selected from among hydrogen peroxide and organic hydroperoxides.

Process for the preparation of oxovinylionol and its O-protected derivatives

The present invention relates to an improved method for producing all-E astaxanthin dimethyldisuccinate of the formula I. 

Method for producing astaxanthin dimethyldisuccinate

A process for preparing carotenoids, in which the process includes reacting a dialkoxy dialdehyde in a double Wittig condensation with a phosphonium salt of or in a double Wittig-Horner condensation with a phosphonate. The carotenoids include, for example, &#x3b2;-carotene, zeaxanthin, canthaxanthin, astaxathin, lycopene and croceptin, which are useful as nutraceuticals, food colorants, and feed additives.

Method for producing carotenoids

The invention relates to a process for preparing chiral imidazolidin-2-ones of the formula I in which in which R, Rand Rhave the abovementioned meaning, with urea in the presence of an involatile ammonium salt, wherein the reaction is carried out in the presence of an aprotic polar organic solvent.

Method for the production of chiral imidazolidin-2-ones

The present invention relates to an improved process for preparing 2,7-dimethylocta-2,4,6-trienedial of the formula I, by  &#x2003;in the presence of a Lewis acid catalyst to give a condensation product of the formula IV,  &#x2003;where the radicals Rand Rin formulae II to IV are independently of one another C-C-alkyl; b) hydrolysis of the acetal groups of IV by adding an aqueous acid to form the dialdehyde of the formula V;  d) crystallization of I from the reaction mixture, Wherein process steps a) to d) are carried out in the presence of an inert, water-immiscible organic solvent.

Method for producing 2,7-dimethyl-octa-2,4,6-trienedial

The invention relates to a process for preparing phytofluene of the formula I, where    where the radicals R, Rand R, and Xand Yhave the meaning sated in the description.

Method for the production of phytofluene

A process for preparing compounds of the formula I is described and entails converting a compound of the formula II by Wittig or Wittig-Horner reaction into a compound of the formula IV, where appropriate converting the compound of the formula IV by hydrolysis of the acetal function and Wittig or Wittig-Horner reaction into a compound of the formula VI and converting the compound of the formula IV or VI in two stages into the compound of the formula I. The radicals R, Rand Rand k have the meaning indicated in the description. Novel intermediates are also described.

Process for preparing polyenedialdehyde monoacetals

Process for the preparation of cis-6-hexadecenoic acid

Process for the preparation of meso-zeaxanthin

Growing community of inventors

Speyer, Germany

Hansgeorg Ernst