Basf Se Corporation

Basf Aktiengesellschaft

Abbott Gmbh & Co Kg

Basf Plant Science Company Gmbh

Hans Wolfgang Hoeffken

Matthias Witschel

Liliana Parra Rapado

Klaus Kreuz

Klaus Grossmann

Thomas Mietzner

Johannes Hutzler

Anja Simon

Thomas Ehrhardt

Frank Stelzer

Tao Qu

Thomas Seitz

Trevor William Newton

Helmut Kraus

Julia Major

William Karl Moberg

Anna Aleksandra Michrowska-Pianowska

Andree Van Der Kloet

Dschun Song

Ruediger Reingruber

Wilfried Hornberger

Bernhard Schmied

Ulrich Mueller

Helmut Mack

Matthias Bratz

Lee Daniel Arnold

Stefan Haefner

Thomas Pfeiffer

Raphael Aponte

Gerhard Cox

Kai-Uwe Baldenius

Richard W Dixon

Heidi Emilia Saxell

Frederick Calo

Harald Bernard

Tilo Habicher

Rainer Packe-Wirth

Emi Leung

Klaus Ruebsamen

Christian Biesgen

Rafel Israels

Wolfgang Koerwer

Andrea Piatesi

Karen Nazaretian Allen

Juergen Reichert

Carsten Schwalb

Hans-Joachim Boehm

Andrea Hlubek

Ansgar Schaefer

Ingo Brode

Elisa Nauha

Maija Nissinen

Li-Wen Wang

Erich Kromm

Nancy J Bump

Cornelia Bellamacina

Michael Bueschel

Juergen Schweden

Manfred Kurfuerst

The present invention relates to a pyrazolopyran of the general formula I wherein the variables are defined according to the description, including a tautomer, salt, cleavable prodrug, or mixtures thereof, in particular to said pyrazolopyran for use as a medicament and/or an inhibitor of the enzyme serinehydroxymethyltransferase (SHMT). The invention also relates to a process the preparation of a pyrazolopyran of the formula I, to compositions comprising said compound and processes for the preparation of these compositions. Further it relates to use of the pyrazolopyran of formula I as an herbicide as well as to a method of controlling undesired vegetation. 

Pyrazolopyrans having herbicidal and pharmaceutical properties

The present invention relates to crystalline complexes of 4-hydroxy benzoic acid and selected pesticides. It also relates to agriculturally useful compositions of the complexes.

Crystalline complexes of 4-hydroxy benzoic acid and selected pesticides

Substituted pyridazines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.

Substituted pyridazines having herbicidal action

Substituted pyridines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N-oxides, their agriculturally suitable salts, compositions comprising them and their use as herbicides, and also methods for controlling unwanted vegetation.

Substituted pyridines having herbicidal action

Substituted pyridazines of the formula I in which the variables are defined according to the description, processes and intermediates for preparing the compounds of the formula I and their N oxides, their agriculturally useful salts, compositions comprising them and their use as herbicides, and also a method for controlling unwanted vegetation.

Pyrazinothiazines having herbicidal action

Pyridothiazines having herbicidal action

The present invention relates to the use of a porous metal organic framework comprising at least a first organic compound and, if appropriate, a second organic compound, in which at least the first organic compound is at least partially coordinated in a bidentate fashion to at least one metal ion, where the at least one metal ion is Mg(II) and the first organic compound is derived from formic acid and the second organic compound is derived from acetic acid, for storing or isolating methane. Furthermore, the invention relates to a porous metal organic framework based on magnesium formate and acetate and also its preparation.

Use of formate-based porous metal organic frameworks for methane storage

The present invention relates to polypeptides which comprise the ligand binding domain of Tie-2, crystalline forms of these polypeptides and the use of these crystalline forms to determine the three dimensional structure of the catalytic domain of Tie-2. The invention also relates to the use of the three dimensional structure of the Tie-2 catalytic domain both alone, or in complex with inhibitors, in methods of designing and/or identifying potential inhibitors of Tie-2 activity, for example, compounds which inhibit the binding of a native substrate to the Tie-2 catalytic domain.

Method of identifying inhibitors of Tie-2

Hirudin/polyalkylene glycol conjugates and hirudin muteins

2-substituted 3-(4-amidinophenyl)propionic acid derivatives

Peptides with anticoagulant activity

Growing community of inventors

Ludwigshafen, Germany

Hans Wolfgang Hoeffken