Active Biotech Ab

Hans Wännman

Karl Erik Jansson

Tomas Fristedt

Anders Björk

Anders K Bjork

Helena Eriksson

Marie Törngren

Andreas Buhl

A plurality of particles of tasquinimod in free base form or as a pharmaceutically acceptable salt, said particles having a D(v, 0.9) of at most 30 pm and a D(v, 0.5) of at most 15 μm. A pharmaceutical composition comprising said particles and preferably one or more pharmaceutically acceptable excipients. A pharmaceutical dosage unit. The particles, composition and dosage unit are useful in the treatment of cancer.

Plurality of tasquinimod particles and use thereof

A stable solid pharmaceutical composition consisting essentially of an effective amount of a crystalline salt of formula (II) together with an alkaline-reacting component maintaining the pH preferably above 8, or a salt with a divalent metal cation; andat least one pharmaceutical excipient;said salt of formula (II) being essentially stable during storage at room temperature for a period of at least 3 years. A process for stabilizing the salt of formula (II). A crystalline salt of formula (II) and a process for preparing said salt.

Crystalline salts of quinoline compounds and methods for preparing them

A stable solid pharmaceutical composition consisting essentially of an effective amount of a salt of formula (II)  A crystalline salt of formula (II) and a process for preparing said salt.

Compositions containing quinoline compounds

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Ängelholm, Sweden

Hans Wännman