Merck Patent Gesellschaft MIT Beschrankter Haftung

Merck Patent Gesellschaft MIT

Eprova Ag Forschungsinstitut

Hans-Rudolf Muller

Heinrich Bollinger

Ulrich Heywang

Alfred Hedinger

Werner Kundig

Method for debenzylation of dibenzylbiotin

The invention relates to a selective process for the preparation of N-L-.alpha.-aspartyl-L-phenylalanine-1-lower alkyl ester which comprises:

Process for the preparation of lower alkyl esters of

A process for the simultaneous production of fructose and of gluconic acid from glucose-fructose mixtures and/or from invert sugar by the selective oxidation of the glucose proportion, wherein oxygen and/or air, activated by noble metal catalysts, are utilized as the oxidizing agents; the oxidation is conducted in a pH range of about 8 to 10; and the oxidation is terminated after the formation of 1 equivalent of carboxylic acid per mole of glucose employed. The thus-obtained gluconic acid can subsequently be separated from the unchanged fructose in a simple way and practically quantitatively, and can be isolated as the salt.

Process for the simultaneous production of fructose and gluconic acid

Growing community of inventors

Schaffhausen, Switzerland

Hans-Rudolf Muller