Dritte Patentportfolio Beteiligungsgesellschaft Mbh &co. Kg

Wolff Cellulosics Gmbh Co. Kg

Leibniz-Institut Für Naturstoff-Forschung Und Infektionsbiologie

Leibniz-institut Fuer Naturstoff-forschung Und Infektionsbiologie

Leibniz-institut Fuer Naturstoff-forschung Und Infektionsbiologie E.v. Hans-knoell-institute (hki)

Helmholtz-zentrum Fur Infektionsforschung Gmbh

Leibniz-institut Für Naturstoff-forschung Und Infektionsbiologie E.v. -hans-knöll-institut- (hki)

Makarov, Vadim

Hans-Martin Dahse

Rolf Müller

Thomas Heinze

Andreas Kirschning

Christian Hertweck

Kathrin Mohr

Michaela Schmidtke

Kirstin Scherlach

Florian Kloss

Axel Brakhage

Ute Möllmann

Martin Roth

Peter Wutzler

Nico Ueberschaar

Vadim Albertovitch Makarov

Albert Härtl

Vera Haack

Thorger Lincke

Keishi Ishida

Swantje Behnken

Hans-Wilhelm Nuetzmann

Mikko Metsae-Ketelae

Sebastian Schieferdecker

Tom Bretschneider

Michael Wolling

Frank Surup

Konrad Viehrig

Mikko Metsae-Ketalae

Vadim Makarov

The present invention relates to novel Chartreusin analogues of formula (I), pharmaceutical compositions comprising the same and to their use for the treatment of cancer and other diseases.

Chartreusin analogues

This invention relates to the field of biologically active compounds and specifically to phaeofungins, of the general formula (I) or a pharmacologically acceptable salt, solvate, hydrate or a pharmacologically acceptable formulation thereof, pharmaceutical compositions comprising these compounds, methods for the production of the phaeofungins and their use as fungicide, antibiotic as well as antitumor agent. 

Benzopyranobenzothiazinones and their use as fungicides, antibiotics and antitumor agents

4-amino-3-arylamino-6-arylpyrazolo[3,4-d]pyrimidine derivatives of general formula (I), pharmaceutically acceptable salts thereof, method for preparation of the aforesaid compounds and their use as antiviral agents. 

4-amino-3-arylamino-6-arylpyrazolo[3,4-d) pyrimidine derivatives, methods for their preparation and their use as antiviral agents

This invention relates to the field of biologically active compounds and specifically to closthioamides, pharmaceutical compositions comprising these compounds, and their use as antibiotic, antifungal, and/or cytotoxic agent.

Closthioamides, compositions, and methods for treating bacterial or fungal infections or cancer

The present invention relates to a method of treating infectious diseases, that involves: (a) providing an alpha-glycosidically linked starch polysaccharide derivative; and (b) inhibiting the growth of an infectious disease by administering a composition comprising the alpha-glycosidically linked starch polysaccharide derivative. The alpha-glycosidically linked starch polysaccharide derivative represented by the following general formula I, in which: the alpha-glycosidically linked starch polysaccharide derivative has a degree of quaternary ammonium group substitution of from 0.4 to 2.0; n is 2-4; Ris selected from the group consisting of Calkyl, benzyl and benzyl substituted with a member selected from the group consisting of Calkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano, dialkylamino and hydrogen; Rand Rare each independently selected from the group consisting of Calkyl, benzyl and benzyl substituted with a member selected from the group consisting of Calkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano and dialkylamino; and X is an anion selected from the group consisting of halide, hydroxide, sulfate, hydrogen sulfate and carboxylate.

Method of treating infectious diseases with polysaccharide derivatives

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Jena, Germany

Hans-Martin Dahse