Bayer Aktiengesellschaft

Bayer Aktiengsellschaft

Hans Lindel

Werner Hallenbach

Friedrich Berschauer

Martin Scheer

Anno De Jong

Heinrich A Greife

Gernot Klotz

Wilhelm Brandes

Klaus Jelich

Gerhard Bonse

Axel Ingendoh

Reinhard Lantzsch

Bernd Gallenkamp

Hans-Joachim Diehr

Guido Steffan

Helmut Kraus

Walter Merz

Gunther Cramm

Christoph Mannheims

The present invention relates to a process for the preparation of 5-substituted 2-chloropyridines of the formula (I) ##STR1## by reaction of acetenamides of the formula (II) ##STR2## with Vilsmeier reagent, which is prepared by reaction of dialkylformamides of the formula (III) ##STR3## with a chlorinating agent, the excess of which is removed from the reaction mixture by distillation or by addition of dialkylformamide after completion of the reaction of the Vilsmeier reagent with the acetenamide of the formula (II), wherein in the formulae (I)-(III):

Process for the preparation of 5-substituted 2-chloropyridines

The invention relates to a novel process for preparing chloromethylpyridines of the general formula (I) ##STR1## in which n represents the numbers 0,1,2 or 3 and

Process for preparing chloromethylpyridines

2-Chloropyridine derivatives of the formula (I) ##STR1## in which R represents hydrogen, C.sub.1 -C.sub.4 -alkyl or halogen and

Process for the preparation of 2-chloropyridines

A compound for promoting livestock production and for controlling obesity in humans and animals, of the formula ##STR1## in which A represents .dbd.CH-- or .dbd.N--,

(2-aminopropyl) pyridines useful as intermediates

A process for the preparation of 2,3-dichloro-5-acetylpyridine of the formula ##STR1## comprising decarboxylating a compound of the formula ##STR2## in which R.sup.1 stands for methyl or ethyl, in a mixture of water and a water miscible aprotic solvent.

Preparation of 2,3-dichloro-5-acetylpyridine

A process for the preparation of 3-trichloromethylpyridine of the formula ##STR1## which comprises reacting 3-methyl-pyridine hydrogen sulphate of the formula ##STR2## with elemental chlorine which exposure to at least one of visible and ultraviolet light at a temperature between about 70.degree. C. and 150.degree. C.

Preparation of 3-trichloromethyl-pyridine

A pyridine derivative of the formula ##STR1## in which A stands for ##STR2## is useful in the preparation of 4-bromo-6-chloro-5-amino-2-pyridyl-ethanolamines, their physiologically tolerated salts and their N-oxides. The 4-bromo-6-chloro-5-amino-2-pyridyl-ethanolamines are useful as yield promoters in animals and as feedstuff additives to achieve higher increases in weight and improved feed utilization.

4-bromo-6-chloro-5-amino-2-substituted pyridyl compounds

Heteroarylethanol-pyridylalkylamines for controlling animal growth

2,4-dihalogeno-6-pyridylethanolphenylisopropylamines for shifting the protein-fat ratio of animals in favor of protein, of the formula ##STR1## in which Hal are identical or different and represent fluorine, chlorine or bromine,

2,4-dihalogeno-6-pyridylethanolphenylisopropylamines for shifting the

##STR1## in which R and R.sup.1 each independently is hydrogen, alkanoyl or alkyl or, together with the adjacent nitrogen atom, form an optionally substituted saturated or unsaturated heterocyclic radical,

Halogen substituted pyridylalkyl ketones

4-Bromo-6-chloro-5-amino-2-pyridyl-ethanolamines, intermediates for preparation thereof and their use as yield promoters for animals and as feedstuff additives to achieve higher increases in weight and improved feed utilization of the formula ##STR1## in which R.sup.1 stands for hydrogen, alkyl, acyl or substituted silyl,

4-bromo-6-chloro-5-amino-2-pyridyl-ethanolamines and their use as yield

Method of promoting the yield and growth of animals which comprises administering to such animals a yield and growth promoting effective amount of a benzimidazole derivative of the formula ##STR1## in which R.sup.1 stands for hydrogen, hydroxyl, alkyl or halogenoalkyl,

Use of benzimidazole derivatives as yield promoters

##STR1## (II), (III), (IV) and (V) are new. (VII) is a known intermediate for an animal growth promoter.

6-ethyl-3-amino or nitro-2,4-dihalogenopyridine compounds

For promoting livestock production, the novel substituted pyridylethanolamines of the formula ##STR1## in which R.sup.1 represents CN, --COOR.sup.8 or --CONR.sup.9 R.sup.10,

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Leverkusen, Germany

Hans Lindel