Stratec Biomedical Ag

Stratec Molecular Ag

Invitek Gesellschaft Für Biotechnik & Biodesign Mbh

Hans Joos

Peter Bendzko

Ralf Griebel

Jens Beator

Birgit Hoeding

Norbert Wendt

Embodiments relate to a lysis buffer mixture that is stable in storage for isolating nucleic acids from biological, preferably diagnostic samples. The mixture is preferably associated with an extraction control. The aim of the invention is to provide an improved nucleic acid extraction system, which is cost-effective, stable and easy to use, thus fulfilling the requirements of a modern nucleic acid extraction system and containing, among other things, extraction controls. Embodiments relate to a lysis buffer mixture for isolating nucleic acids, said mixture containing non chaotropic salts, a special selection of detergents, a defined quantity of at least one nucleic acid as an extraction control, optionally lytic enzymes, optionally carrier nucleic acids and optionally other additives.

Stable lysis buffer mixture for extracting nucleic acids

Described is a system for the stabilization, conservation and storage of a nucleic acid, wherein the system comprises a test tube and a preferably freeze-dried stabilization mixture. Upon addition of a viscous bodily fluid to the mixture, the mixture dissolves and stabilizes the nucleic acid present in the bodily fluid.

System for the stabilization, conservation and storage of nucleic acid

The invention relates to a purification method for high-purity, DNA-free RNA using a mixture of nanocarrier beads and paramagnetic beads.

Method for isolating high-purity RNA by means of paramagnetic microparticles and nanoparticles

The invention comprises an apparatusand a methodfor purifying biomolecules. Magnetizable particlesand a group of magnetizable pinsare used for binding biomoleculesto the magnetizable particlesusing a binding buffer, and for transferring the magnetizable particlesforming a particle-biomolecule complex. The apparatuscomprises an incubation unitthat allows for an upscaling of a maximum volume of a sample material. Furthermore the apparatuscomprises counter magnetswhich are arranged on cavities. Solutionscomprising the biomoleculesand the magnetizable particlesare disposed in the cavities. The use of counter magnetsimproves the quality of an eluate. Furthermore the invention comprises a systemand a methodfor a diagnostically purifying of biomolecules. The methodfurther comprises a controlling of method steps and a selection of substances and reagents (for example the magnetizable particles) based on information automatically collected from, for example, the samples and/or derived from used substances and reagents. The systemfulfills requirements of medical diagnostics.

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Berlin, Germany

Hans Joos