Forschungszentrum Juelich Gmbh

Universitaet Zu Koeln

Anm Adaptive Neuromodulation Gmbh

Forschungszentrum Julich Gmbh

UniversitÄt Zu Koln

Hans-Joachim Freund

Peter Alexander Tass

Urban Schnell

Jean-Christophe Roulet

Oleksandr Popovych

Birgit Utako Barnikol

Joel Niederhauser

Volker Sturm

Joël Niederhauser

A device and method for desynchronizing a patient's neuronal brain activity in which the neuron population is firing in a pathologically synchronized manner. The device includes a stimulation unit that generates an acoustic stimulation signal that includes both a first tone and a second tone. The first tone is provided to shift the phase of the neuronal brain activity of a first subpopulation of the neuron population relative to the phase of the neuronal brain activity of a second subpopulation of the neuron population when the first tone is acoustically received by the patient. Further, the second tone is provided to shift the phase of the neuronal brain activity of the second subpopulation relative to the phase of the neuronal brain activity of the first subpopulation when the second tone is acoustically received by the patient. As a result, the acoustic stimulation signal desynchronizes the stimulated neuron population.

Device and method for auditory stimulation

A device and method for desynchronizing a patient's neuronal brain activity involving a neuron population firing in a pathologically synchronized manner. The device includes a stimulation unit configured to generate an acoustic stimulation signal to stimulate the neuron population when the acoustic stimulation signal is aurally received by the patient. Furthermore, the acoustic stimulation signal has a first frequency and a second frequency, with the first frequency provided to reset the phase of the neuronal brain activity in a first sub-population of the stimulated neuron population, and the second frequency provided to reset the phase of the neuronal brain activity in a second sub-population of the stimulated neuron population.

A description is given of a method to treat dementia, in particular Alzheimer's disease, Lewy body dementia and vascular dementia, by means of electrical brain stimulation.

Method for treating dementia

Growing community of inventors

Ratingen, Germany

Hans-Joachim Freund