Bayer Aktiengesellschaft

Hans-J&uuml;rgen Hamann

Bernd Klinksiek

J&uuml;rgen Sdebik

Said Mahiout

Ricarda-Christine Nothelle

In the procedure for the production of a formulation of parenterally administrable pharmaceutical preparations, a liposome dispersion is used as a carrier for a pharmaceutical active compound. For the preparation of the liposome dispersion, an aqueous predispersion of one or more amphiphilic substances is fed to a high-pressure homogenizer in which the predispersion is pumped under a pressure from 600 bar to 900 bar through a homogenizer nozzle (,) having a diameter of 0.1 to 0.5 mm. The homogenizer nozzle has an inlet channel (,) and an outlet channel (,) and consists of a hard ceramic plate (,), in which the bore (,) is present, pressed into a steel body (,). The inlet channel (,) and the outlet channel (,) are likewise incorporated into the steel body (,).

Growing community of inventors

Dormagen, Germany

Hans-Jürgen Hamann

Growing community of inventors

Dormagen, Germany

Hans-J&uuml;rgen Hamann

Hans-Jürgen Hamann