Hoechst Aktiengesellschaft

Max-planck-gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Hans-Georg Rammensee

Gunther Jung

Karl-Heinz Wiesmuller

Karl Deres

Stefan Stevanovic

Olaf Rotzschke

Hansjorg Schild

Kirsten Falk

According to certain embodiments, the invention relates to an immunoconjugate produced by conjugating at least one membrane-anchoring compound with at least one partial sequence of a protein of a virus, a bacterium, a parasite or a tumor antigen. The immunoconjugate has the advantage that it can be stored for a very long time even without cooling. According to certain embodiments, the invention relates to an immunogenic composition for the specific induction of cytotoxic T-lymphocytes which comprises a conjugate from at least one membrane anchor compound and a protein, containing at least one killer T-cell epitope, of a virus, a bacterium, a parasite or a tumor antigen, or at least one partial sequence containing at least one killer T-cell epitope of a viral, bacterial or parasite protein or of a tumor antigen.

Membrane anchor/active compound conjugate, its preparation and its uses

Determination of peptide motifs on MHC molecules

Growing community of inventors

Tubingen, Germany

Hans-Georg Rammensee