Agilent Technologies, Inc.

Hewlett-packard Company

Hewlett-packard Corporation

Hans-Georg Haertl

Klaus E Witt

Kent D Vincent

Terry A Berger

Konstantin Shoykhet

Konstantin Choikhet

Joachim-Richard Wagner

Joachim Wagner

A sealing configuration is configured for sealingly coupling a first fluid flow path of a first device to a second fluid flow path of a second device. The sealing configuration comprises a contact surface comprising a structure configured for increasing a surface pressure when coupling the first device to the second device. The contact surface comprises a metal coating configured for increasing sealing.

Sealing configuration with metal-coated structure

A filter for filtering debris out of a fluid flowing along a fluid flow direction in a fluidic member of a sample separation device, the filter comprising a plurality of filter structures stacked along the fluid flow direction and each having pores with defined pore size, wherein the defined pore size of the stacked filter structures decreases along the fluid flow direction.

Debris filter for fluidic measurement with recess size decreasing in fluid flow direction

A fluid supply system () adapted for metering two or more fluids in controlled proportions and for supplying a resultant mixture, the fluid supply system () comprising a plurality of solvent supply lines (to), each fluidically connected with a fluid source (to) providing a respective fluid, a pumping unit () comprising a reciprocating element () adapted for intaking fluid supplied at an inlet of the pumping unit () and for supplying the pressurized fluid at an outlet of the pumping unit (), wherein the pumping unit () is adapted for taking in fluids from selected solvent supply lines (to) and for supplying a pressurized mixture of the fluids at its outlet, a proportioning valve () interposed between the solvent supply lines (to) and the inlet of the pumping unit (), the proportioning valve () adapted for modulating solvent composition by sequentially coupling selected ones of the solvent supply lines (to) with the inlet of the pumping unit (), and a longitudinal mixing unit () adapted for mixing longitudinally subsequent sections of the fluids so as to modify their succession in flow direction.

Packet-wise proportioning followed by immediate longitudinal mixing

The volumetric flow rate of a fluid is determined essentially independently of the properties of the fluid by guiding the volumetric fluid flow to be measured through an essentially linear flow resistor. An alternating flow of the fluid is superimposed on the volumetric fluid flow to be measured. Steady and alternating components of a pressure drop across the flow resistor are detected. A quantity representative of a property of the fluid is determined in response to the determined alternating component. The volumetric flow rate is calculated on the basis of the determined steady component and the quantity representing fluid property.

Fluid sensor including substantially linear flow resistor

A pumping system for pumping fluids at sub-ambient temperatures where the pumping fluid, after it has been used for its analytical application, is expanded such that the energy of expansion of the pumping fluid can be employed for cooling the pump head or pumping fluid prior to pumping.

Analytical system having energy efficient pump

A new mechanism for pulsation damping in a reciprocating diaphragm pump system is disclosed which is especially suitable for solvent delivery in modern high pressure liquid chromatography requiring a wide range of solvent flow rates and pressures. The disclosed damper has good overall performance over the full range of liquid chromatographic conditions, a dead volume independent of solvent pressure, and largely eliminates the necessity for continuously pumping the working oil of the diaphragm pump to a maximum operating pressure.

Growing community of inventors

Karlsruhe, Germany

Hans-Georg Haertl