General Electric Company

Ge Medical Systems Global Technology Company, LLC

G.e. Vingmed Ultrasound As

Vingmed Sound A/s

Cimon Medical As

Norwegian University of Science and Technology

Hans Garmann Torp

Andreas Heimdal

Steinar Bjaerum

Bjorn Olstad

Kjell Kristoffersen

Lasse Lovstakken

Torbjorn Hergum

Sigmund Frigstad

Fredrik Orderud

Johan Kirkhorn

Erik Normann Steen

Bjorn A Angelsen

Svein Arne Aase

Stein Inge Rabben

Jean-Francois Gelly

Kjell Kristofferson

Vidar Lundberg

Kjetil Viggen

Svein Brekke

Sebastien Salles

Bj&oacute;rn Olstad

Steinar Bj&aelig;rum

Dagfinn Saetre

Torbjørn Hergum

Tore Gruner Bjastad

Gard Hagen

Charlotte Björk Ingul

The invention provides a method of monitoring blood flow in a vertebrate animal subject. Unfocussed plane-wave ultrasound pulses are transmitted into the subject, along a transmission axis, from a single-element ultrasound transducer () fastened to the subject (). Reflections of the ultrasound pulses are received, generating a succession of pulse-Doppler response signals over time. Each pulse-Doppler response signal is processed to determine a first respective spatial-maximum velocity value for blood flowing towards the single transducer element (), and a second respective spatial-maximum velocity value for blood flowing away. Heartbeats are identified from said spatial-maximum velocity values and a quality metric is assigned to each identified heartbeat. A subset of the spatial-maximum velocity values is identified for which the assigned quality metric exceeds a threshold level. The values from the subset are monitored, and, when a set of values from the subset satisfies a predetermined alert criterion an audible or visual alert is signalled.

Ultrasound blood-flow monitoring

A system for monitoring blood flow in a patient, the system comprising: a single-element disc-shaped ultrasound transducer for fastening to the patient and a controller subsystem. The controller subsystem is configured to: control the ultrasound transducer to transmit a series of plane-wave pulses into the patient in a propagation direction; sample reflections of the plane-wave pulses, received at the ultrasound transducer, from a region within the patient, to generate pulse-Doppler response signals; and process the pulse-Doppler response signals to calculate a blood flow curve for waveform analysis.

A method of processing cardiac ultrasound data for determining information about a mechanical wave in the heart. The method comprises receiving data representative of a time series of three-dimensional data frames, generated from ultrasound signals from a human or animal heart, each frame comprising a set of voxels, each voxel value representing an acceleration component of a respective location in the heart at a common time. The method also comprises identifying, for each voxel, a frame of the series in which the voxel value is at a maximum. A three-dimensional time-propagation data set is generated by assigning each voxel a value representative of the time of the respective frame in the time series for which the corresponding voxel is at a maximum. The method then comprises generating data representative of a three-dimensional velocity vector field by calculating time derivatives from the three-dimensional time-propagation data set.

Ultrasound cardiac processing

A system for monitoring blood flow in a patient comprises a first unit having an ultrasound transducer and a fastener for fastening the unit to the patient. A controller subsystem comprises the first unit and a separate second unit. The controller subsystem is configured to: control the ultrasound transducer to transmit plane-wave pulses into the patient in a propagation direction; sample reflections of the plane-wave pulses, received at the ultrasound transducer, from a region within the patient, to generate pulse-Doppler response signals; and process the pulse-Doppler response signals to estimate a series of values, over time, of a measure proportional, but not equal, to the total blood volume flow passing through the region. A monitoring subsystem is configured to monitor the series of values over time and to generate a signal if a set of one or more of the values satisfies a predetermined criterion.

An ultrasound imaging method in which ultrasound signals are transmitted into a living organism, reflected from fluid flowing along a path within the organism, and received by an ultrasound transceiver system with a resolution limit in a first direction. These signals are used to generate data representing a sequence of images over time; each image including a speckle pattern arising from interference within the reflected ultrasound signals. A peak-sharpening operation is applied to the image data, generating data representing a sequence of resolution-enhanced images, each having a resolution in the first direction finer than the resolution limit of the transceiver system in that direction, and including a respective peak-sharpened speckle pattern. A combining operation is applied to generate data representing an output image in which the path of the fluid is represented by a superimposition of the peak-sharpened speckle patterns from the resolution-enhanced images.

Enhanced-resolution ultrasound imaging of fluid paths

An acquisition component is provided that includes an audible sound sensor configured to receive audible sounds within a sensing area and a multi-element ultrasound transducer configured to emit ultrasound signals and to receive reflections of the ultrasound signals in the same sensing area. The audible sound sensor and the multi-element ultrasound transducer may be configured to be simultaneously operable.

Methods and apparatus for combined audible and ultrasound inspection of objects, including patients

Certain embodiments of the present technology provide systems and methods that provide reduction of multiline artifacts in Doppler imaging. Certain embodiments provide for various ensembles of transmit beams at different spatial locations and overlapping receive beams between the locations. Certain embodiments provide for calculating various auto-correlation estimates based on the received beams and then combining the auto-correlation estimates to create an image. In certain embodiments, combining the auto-correlation estimates comprises applying a linear interpolation filter that decreases the weight applied for receive beams that are spatially located further away from the transmit beam.

Reduction of multiline artifacts in doppler imaging

A method is provided for automatically identifying image views in a three-dimensional dataset comprises accessing with a processor a three-dimensional dataset comprising a plurality of image frames and fitting with the processor at least one deformable model to at least one structure within each of the image frames. The method further comprises identifying with the processor at least one feature point within each of the image frames based on the at least one deformable model and displaying on a display at least one image view based on the at least one feature point.

Method and apparatus for automatically identifying image views in a 3D dataset

A method and system for determining contact along a surface of an ultrasound probe are provided. The method includes frequency analyzing ultrasound signals received by the ultrasound probe and displaying indicators of acoustic contact of the ultrasound probe with an object based on the frequency analysis.

Method and system for determining contact along a surface of an ultrasound probe

An ultrasound system and method for calculation and display of tissue deformation parameters are disclosed. The tissue deformation parameter strain is also determined by an accumulation of strain rate estimates for consecutive frames over an interval. The interval may be a triggered interval generated by, for example, an R-wave in an ECG trace. The strain calculation may be improved by moving the sample volume from which the strain rate is accumulated from frame-to-frame according to the relative displacement of the tissue within the original sample volume. The relative displacement of the tissue is determined by the instantaneous tissue velocity of the sample volume.

Method and apparatus for providing real-time calculation and display of tissue deformation in ultrasound imaging

A method and apparatus for detecting cardiac events. Ultrasonic data comprising a heart cycle is acquired by a probe. Tissue velocities associated with the ultrasonic data are detected. One of a maximum and a minimum value is detected based on the tissue velocities. A time within the heart cycle associated with the maximum or minimum value is determined, and a cardiac event is detected with respect to the time within the heart cycle and the maximum or minimum value.

Method and apparatus for detecting cardiac events

An ultrasound system and method for calculation and display of tissue deformation parameters are disclosed. The tissue deformation parameter strain is determined by an accumulation of strain rate estimates for consecutive frames over an interval. The interval may be a triggered interval generated by, for example, an R-wave in an ECG trace. Three quantitative tissue deformation parameters, such as tissue velocity, tissue velocity integrals, strain rate and/or strain, may be presented as functions of time and/or spatial position for applications such as stress echo. For example, strain rate or strain values for three different stress levels may be plotted together with respect to time over a cardiac cycle. Parameters which are derived from strain rate or strain velocity, such as peak systolic wall thickening percentage, may be plotted with respect to various stress levels.

A trigger extraction system for obtaining an event trigger for an event occurring in a region of interest includes a processor, a memory coupled to the processor, and a trigger extraction program stored in the memory for execution by the processor. The trigger extraction program includes instructions for accessing ultrasound trigger data from a trigger region intersecting a region of interest, analyzing the trigger data for a trigger characteristic, and storing an event trigger based on the trigger characteristic.

Trigger extraction from ultrasound doppler signals

An ultrasound system and method for calculation and display of tissue deformation parameters are disclosed. A method to estimate a strain rate in any direction, not necessarily along the ultrasound beam, based on tissue velocity data from a small region of interest around a sample volume is disclosed. Quantitative tissue deformation parameters, such as tissue velocity, tissue velocity integrals, strain rate and/or strain, may be presented as functions of time and/or spatial position for applications such as stress echo. For example, strain rate or strain values for three different stress levels may be plotted together with respect to time over a cardiac cycle.

A method and apparatus for generating ultrasound pulses comprises producing a multi-level pulse sequence including a series of pulses. The series of pulses includes at least three pulses having three different amplitudes, respectively. The amplitudes are at least one of a positive non-zero voltage, a negative non-zero voltage, and an intermediate level voltage. The multi-level pulse sequence may be produced by a switch network having at least three different input voltage levels. The switch network outputs the multi-level pulse sequence at an output node to a transducer within a probe. Echo signals based on the series of pulses are received, and an ultrasound image is produced based on the received echo signals.

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Trondheim, Norway

Hans Garmann Torp