Kabigen Ab

Other

The Rockefeller University

Mabtech Ab

Commerceguard Ab

Skandigen Ab

All Set Marine Security Ab

Hans G Boman

Viktor Mutt

Hans Jornvall

Robert B Merrifield

Mats Andersson

Jong-Youn Lee

Hakan Steiner

Torgny Rasmuson

Dan Hultmark

Karl Bohman

Stig Ekström

David Andreu

Eric Sandberg

Katrin Pütsep

Göran Carlsson

Magnus Cederlöf

G R Mortenson

David Wade

A method for determining the susceptibility of a subject to infection, which method comprises: (i) providing a sample from said subject; (ii) detecting any LL-37 present in said sample; (iii) optionally comparing the level of LL-37 in said sample to a control sample; and (iv) determining the susceptibility of said subject to infection, wherein no LL-37 or a low level of LL-37 indicates that said subject is susceptible to infection.

Method for determining the susceptibility of a subject to infection

A container and contents monitoring system includes a device, a reader, a server, and a software backbone. The device communicates with the reader in order to determine the security and/or location of the container to which the device is attached. The reader transmits the information from the device to the server. The device determines if a security condition has occurred based on at least one sensor located on or in the container.

Method and system for monitoring containers to maintain the security thereof

A container and contents monitoring system includes a device, a reader, a server, a software backbone and a receptacle for housing a plurality of sensors. The device communicates with the plurality of sensors and the reader in order to determine the condition of the container and its contents. The reader transmits the information from the device to the server. The device determines if a container condition has occurred based on at least one sensor located on or in the container.

Method and system for utilizing multiple sensors for monitoring container security, contents and condition

78 residue polypeptide (NK-lysine) and its use

The invention relates to antibacterial and antimalarial peptides which are hybrids peptides which a of naturally occurring peptides such as cecropins, attacins, magainins, sarcotoxin, sapecin, bactenecins, alamethidicins, defensins and PGLa, and toxins such as streptolysins, melittin, barbatolysin, paradaxins and delta hemolysin. The hybrid peptides of the present invention are easily synthesized and have reduced toxicity. Also included in the invention are pharmaceutical compositions containing such hybrid peptides, and methods of treating patients infected with an organism against which these peptides are active.

Antibacterial and antimalarial hybrid peptides

Antibiotically and/or antimalarially active D-peptides of naturally occurring antibiotics such as cecropin A, B and D, melittin, and Magainin I and II and their addition, deletion and replacement analogs including homologous and heterologous analogs thereof.

Antibiotic peptides containing D-amino acids

Polypeptides and their use

A polypeptide having bactericidal activity, particularly against gram-negative bacteria, has been isolated from pig intestine. The porcine cecropin has the amino acid sequence: H.sub.2 N-Ser-Trp-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-AlaLys-Lys-Arg-Ile-S er-Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg-COOh. Pharmaceutical compositions containing such poypeptides, or functional derivatives thereof, are useful in therapeutic and prophylactic methods for inhibiting bacterial growth.

Antibacterial polypeptides

A non-lysozyme highly active bacteriolytic protein which is heat stable and has a relatively low molecular weight. The protein may be produced by immunizing an insect against E. coli and recovering the protein from the insect. The protein is useful for extracting proteins from genetically engineered bacteria and as a pharmaceutical for inhibiting certain bacteria.

Bacteriolytic proteins

A non-lysozyme highly active bacteriolytic protein which is heat stable and has a relatively low molecular weight. The protein may be produced by immunizing an insect against E. coli and recovering the protein from the insect. The protein is useful for extracting proteins from genetically engineered bacteria and as a pharmaceutical.

Growing community of inventors

Stockholm, Sweden

Hans G Boman