Hoechst Aktiengesellschaft

Hans G Alpermann

Ulrich Stache

Hermann J Gerhards

Klaus-Dieter Kampe

Herbert Siegel

Werner Fritsch

Patricia Usinger

Martin Bickel

Volker Teetz

Wolfgang Raether

Rolf Geiger

Burkhard Sachse

Karl Geisen

Walter Durckheimer

Ulrich Gebert

Walter Dittmar

Jurgen K Sandow

Friedrich-Johannes Kammerer

Wulf Merkel

Walter Petri

Ulrich Schacht

Margret Leven

Walter Ried

Norbert Kothe

The disclosed invention includes corticoid-17-alkylcarbonates substituted in the 17-position, a process for their preparation and pharmaceuticals containing them. These corticoid-17-alkylcarbonates have the following formula I ##STR1## where A is CHOH in any desired steric arrangement, C.dbd.O or CH.sub.2 ; Y is H, F, or Cl; Z is H, F or CH.sub.3 ; R(1) is O-acyl, carbonylalkyl, alkylsulfonate or arylsulfonate;

Corticoid-17-alkyl-carbonates substituted in the 17-position, process

1-(1-Aryl-2-hydroxyethyl)-imidazoles and salts thereof, processes for the preparation thereof, medicaments containing these compounds, and the use thereof. The invention relates to 1-(1-aryl-2-hydroxyethyl)-imidazoles of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, Q, W, X and Y have the meanings specified, and also to medicaments based on these compounds, in particular those having an antimycotic and an antidepressive action.

1-(1-aryl-2-hydroxyethyl)-imidazoles and salts thereof, medicaments

Arylmethylazoles of the formula I ##STR1## in which Aryl is (substituted) phenyl or naphthyl;

Arylmethylazoles and their salts, processes for their preparation,

Peptide amides and process for their manufacture

What is disclosed are steroid-21-halogeno-17-(alkyl carbonates), useful as medicaments for the treatment of inflammatory dermatoses, and a method for making them.

Corticoid-17-(alkyl carbonates) and process for their manufacture

Pyrano-heterocycles of the formula ##STR1## in which R.sup.1 represent hydrogen or an alkyl radical containing up to 4 carbon atoms; R.sup.2 represents hydrogen or an alkyl, alkoxy or haloalkyl radical each having up to 3 carbon atoms, or halogen; or R.sup.1 and R.sup.2 together form an ethylene or propylene group, and R.sup.3 and R.sup.4, independently of each other, are hydrogen or alkyl or alkoxy radicals each of which groups containing up to 3 carbon atoms, which may be unsubstituted or substituted totally or partially with halogen atoms, halogen or alkoxycarbonyl having up to 3 carbon atoms in the alkyl group and R.sup.5 represents a nitro group or hydrogen, their physiologically tolerated salts, processes for preparing these compounds and medicaments containing these compounds.

Pyrano-heterocycles and medicaments containing these compounds

What is disclosed is corticoid 17-(alkyl carbonates) of the formula ##STR1## as defined in the specification, which compounds can be used in veterinary therapy and human therapy, in the form of suspensions, ointments, creams, sprays and the like, for the treatment of inflammatory dermatoses of very diverse cause.

Corticoid 17-(alkyl carbonates) and processes for their preparation

(2-Amino-4-quinazolinyl)-quanidines of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and n have the defined meanings, and their physiologically tolerable acid addition salts, process for preparing these compounds, pharmaceutical preparations containing them and their use as medicines.

4-Quinazolinyl-guanidines

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Konigstein, Germany

Hans G Alpermann