Boston Scientific Scimed, Inc.

Sadra Medical, Inc.

Promed, Inc.

Intuitive Surgical Operations, Inc.

Advanced Cardiovascular Systems, Inc.

Tenon Medical, Inc.

Sadra Medicl, Inc.

Hans F Valencia

Amr Salahieh

Dwight P Morejohn

Ulrich R Haug

Brian D Brandt

Robert Adam Geshlider

Jean-Pierre Dueri

Tom Saul

Jeff A Krolik

Scott A Yerby

Richard S Ginn

Nicanor Domingo

Claudio Argento

Robert Elliott DeCou

Daniel K Hildebrand

Kenneth J Michlitsch

Amnon Yadin

Joseph R Callol

Robert Elliot DeCou

Carolyn M Fenech

W Stan Wilson

Nazanine Matin

Daniel J Gregorich

Andrzej M Malewicz

Serena H Wong

Adam Jennings

Steve Bigus

David Chi

Benjamin G Cohn

Brenda Cho

A method comprises deploying a tool to a passageway exit site through a lumen of a flexible elongate device. The flexible elongate device comprises a proximal end, a distal end, and the lumen therebetween, and the tool comprises a needle. The method further comprises puncturing a passageway wall at the passageway exit site with the needle. The method further comprises deploying the needle through the passageway wall and through target tissue at a target location beyond the passageway wall. The method further comprises deploying an instrument to perform treatment on the target tissue at the target location. The instrument is deployed within the tool and through a perforation created in the target tissue by the needle.

Systems and methods of steerable elongate device

An axial support structure for a flexible elongate device may comprise a plurality of rigid links coupled by pin joints. Each of the plurality of rigid links may comprise a shaft, a pair of male joint connectors, and a pair of female joint connectors. Each male joint connector may comprise a male tab including an inner surface coplanar with an inner surface of the shaft and extending axially from a first end of the shaft. Each of the male joint connectors may include a pin extending radially. Each female joint connector may comprise a female tab having an outer surface coplanar with an outer surface of the shaft and extending axially from a second end of the shaft. The pair of female joint connectors may be rotated by 90 degrees relative to the pair of male joint connectors. Each female tab may define an aperture.

Axial support structure for a flexible elongate device

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.

Replacement valve and anchor

The present invention provides apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion.

Everting heart valve

The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.

Methods and apparatus for endovascularly replacing a heart valve

Configurations are described for conducting minimally invasive medical interventions utilizing elongate instruments and assemblies thereof to stabilize and/or fixate a sacro-iliac joint. In one embodiment, a tool assembly may be advanced from a posterior approach into the SI junction and configured to create a defect defined at least in part by portions of both the sacrum and the ilium, the defect having a three dimensional shape defined in part by at least one noncircular cross sectional shape in a plane substantially perpendicular to the longitudinal axis of the tool assembly. After a defect is created, the tool assembly may be retracted and a prosthesis deployed into the defect.

Method for sacro-iliac stabilization

System for sacro-iliac stabilization

An axial support structure for a flexible elongate device includes a plurality of rigid links. each link comprises a shaft, a pair of male joint connectors comprising a male tab coplanar with the shaft extending from a first end, and a pair of female joint connectors comprising a female tab coplanar with the shaft extending from a second end. Each of the male joint connectors includes a pin extending from the male tab in a direction perpendicular to an axial direction of the shaft and each female tab defines an aperture. Each of the plurality of rigid links is rotated bydegrees with respect to neighboring links among the plurality of rigid links, thereby aligning each pair of male joint connectors with a neighboring pair of female joint connectors to form pin joints in which each aperture encircles a corresponding pin.

A replacement heart valve assembly including an expandable anchor having a skirt region, a lip region, and a groove region therebetween and a replacement valve disposed within the expandable anchor and engaged with the groove region of the expandable anchor.

Repositionable heart valve

The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system.

Systems and methods for delivering a medical implant

The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.

Methods and apparatus for endovascularly replacing a patient's heart valve

Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.

Low profile heart valve and delivery system

Growing community of inventors

Berkeley, CA, United States of America

Hans F Valencia