Astra Lakemedel Aktiebolag

Astra Lakemedel Akteibolag

Hans E Strom

Thomas Hogberg

Lars George Johansson

Sven O Gren

Sten I Ramsby

Karl S Bengtsson

Tomas DePaulis

Marianne E Widman

Hans-Jurgen Federsel

Stereoconservative method for preparation of an (R)- or (S)-isomer of the compound of the formula I with at least 95% optical purity ##STR1## wherein R.sup.1 is a hydrogen atom, a saturated or unsaturated lower alkyl group, a cycloalkyl group, or a group (CH.sub.2).sub.m Ph wherein m is 0-3 and Ph is a substituted or unsubstituted phenyl group including

Efficient stereoconservative synthesis of 1-substituted (S)- and

Novel therapeutically active compounds of the formula ##STR1## wherein Z.sup.i, being Z.sup.1, Z.sup.2 or Z.sup.3, is the same or different and selected among OH, OR.sup.1, NH.sub.2, NR.sub.2.sup.4, NHR.sup.4, SH, SR.sup.4 and OR.sup.4 wherein R.sup.1 is a formyl group, an acyl group, an alkoxycarbonyl group or a mono- or dialkylcarbamoyl group and R.sup.4 is a lower alkyl group,

Oxysalicylamido derivatives

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Jarna, Sweden

Hans E Strom