Merck Patent Gesellschaft MIT Beschrankter Haftung

Hans Dieter Orth

Norbert Hennrich

Michael Klockow

Wolfgang Brummer

Hermann Lang

Gerhard Pfleiderer

Isoenzyme patterns of an enzyme in biological fluids, extracts, and/or excretions are quantitatively determined by precipitating at least 90% of an isoenzyme antigen with a corresponding heterologous antiserum and comparing the remaining enzyme activity with the total activity with the use of a conventional agent for enzyme activity determination.

Analysis of isoenzyme patterns

Biochemically active compounds e.g., proteins and particulate biological materials such as bacteria and viruses, are immobilized on a water-swellable or water-insoluble matrix by covalent bonding to a partially crosslinked polymer containing reactive groups capable of binding the biochemically active compound thereto.

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Darmstadt, Germany

Hans Dieter Orth